Results 51 to 60 of about 28,950 (253)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Elimination of current spikes in buck power converters [PDF]
, 1981 Current spikes in a buck power converter due to commutating diode turn-off time are eliminated by using a tapped inductor in the converter with the tap connected to the switching transistor. The commutating diode is not in the usual place, but is instead
Mclyman, W. T.
core +1 more source
, 2017 We developed a novel magnetic coupling module formed of a monolayer superconducting flux concentrator, which is integrated with a coplanar resonator strongly coupled to HTS rf-SQUID. Three types of resonators, including a long stripline resonator between
Fardmanesh, Mehdi +3 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Analytical Selection of Leakage Inductance for Single-Phase Dual Active Bridge Converters
Applied SciencesThe single-phase dual active bridge (DAB) DC/DC converter is a vital component in modern power electronics systems, facilitating efficient bidirectional power transfer between various energy sources and loads. One of the critical aspects in the design of
Hamid Naseem, Jul-Ki Seok
doaj +1 more source
Mathematical model analysis of new-type magnetic integrated CRT considering magnetic leakage
Journal of Measurement Science and Instrumentation, 2022 A novel magnetic integrated controllable reactor of transformer type (CRT) has the advantages of simple structure, flexible assembly, convenient maintenance and practicability.
WANG Tiange +2 more
doaj
IEEE Access, 2019 When the end leakage flux or end leakage inductance cannot be ignored in a permanent magnet (PM) machine (e.g., a PM machine with a short axial length), the analysis of the machine is a time-consuming three-dimensional (3-D) issue.
Xianbao Chen +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Stability analysis of electric power systems for ‘more electric’ aircraft [PDF]
, 2008 This paper presents a comprehensive assessment of small-signal stability for a “more-electric” aircraft power system consisting of a synchronous variable-frequency generator which supplies several power electronic controlled loads via an 18-pulse ...
Griffo, Antonio, Howe, D., Wang, J.B.
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