Results 81 to 90 of about 221,276 (349)

Coexistence of the BRC Standard for Packaging and the Lean Manufacturing methodology

Engineering Management in Production and Services, 2018
This study aimed to explore the potential impact of the Lean Manufacturing methodology on the implementation and functioning of the BRC Standard for Packaging.
Urban Wiesław, Ratter Emil, Wangwacharakul Promporn, Poksinska Bonnie   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A new lean change methodology for small & medium sized enterprises [PDF]

, 2010
SMEs find it difficult to implement productivity improvement tools, particularly those associated with Lean Manufacturing. Larger companies have more success due to greater access to resources. To provide the SMEs with a way to implement Lean sustainably,
April, Joris, Bart, Schanssema, Powell, Daryl   +2 more
core   +1 more source

Lean tools and techniques: a comparison between Malaysian manufacturing and services organisations [PDF]

, 2018
The purpose of this study is to compare lean tools and techniques in terms of the awareness, usage, effectiveness and potential future adoption between Malaysian manufacturing and services organisations in order to help Malaysian organisations to select,
Mohammad, Musli, Omar, Badrul, Ramly, Edly Ferdin, Yahya, Mohd Shahir   +3 more
core   +1 more source

Metodología para incrementar la productividad del proceso productivo en una mype metalmecánica de producción de Tees utilizando Lean Manufacturing, Systematic Layout Planning y TOPSIS [PDF]

, 2023
Jon Arambarri, Fernando Abad Cairo Tineo, Marian Gemma Condori Dávila, Cynthia Carola Elías Giordano, José Rojas   +4 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Réalisation de modules de formation au lean manufacturing [PDF]

, 2008
Le concept de GéoLean est basé sur la mise en pratique du Lean Manufacturing. Pour mieux comprendre ses origines et l’état d’esprit dans lequel travaille la société, il est indispensable de revenir aux sources du Lean Manufacturing, c'est‐à‐dire de ...
Latorre García de la Santa, Ester, Villate Pérez, Irati   +1 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Lean management in a non-manufacturing organization

Ekonomski Vjesnik, 2013
This paper examines the possibilities of a lean approach to non-manufacturing functions, i.e. a market-oriented organization. This refers to purchasing, shipment, storage, sale and delivery of goods; marketing, etc.
Mladen Žvorc
doaj  

APLICAÇÃO DE FERRAMENTAS LEAN MANUFACTURING PARA MELHORIA DE PERFORMACE EM MAQUINA EM UMA INDÚSTRIA DO SETOR DE ALUMÍNIO [PDF]

, 2023
RENATA MACIEL DE MELO, ANNE JULIA DE LIMA SILVA, CRISTINA PEREIRA MEDEIROS, LAÍS LOPES DA SILVA, Thalles Vitelli Garcez   +4 more
openalex   +1 more source