Results 61 to 70 of about 134,821 (385)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Lean Six Sigma Leadership in Health Care Organizations [PDF]
, 2017 The reason for choosing this topic was the want to change the current employee settings in health care organizations. Using Lean Six Sigma Leadership has been a proven method to increasing staff satisfaction and empowering lifelong learning. The research
Bittles, Natalie
core +2 more sources
Lean six sigma 4.0 methodology for optimizing occupational exams in operations management
International Journal of Lean Six SigmaPurpose This paper explores Lean Six Sigma principles and the DMAIC (define, measure, analyze, improve, control) methodology to propose a new Lean Six Sigma 4.0 (LSS 4.0) framework for employee occupational exams and address the real-world issue of high-
Tatiana da Costa Reis Moreira +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Lean Six Sigma and marketing: a missed opportunity [PDF]
, 2014 Purpose – The purpose of this paper is to assess the current use being made of the sustainability message within business improvement activity and project justification within individual businesses.
Chaplin, Lara, O'Rourke, Simon T.J.
core +1 more source
Industry 4.0 and Lean Six Sigma Integration: A Systematic Review of Barriers and Enablers
Applied Sciences, 2022 In recent years, Industry 4.0 (I4.0) has been a recurrent theme in the literature on Lean Six Sigma (LSS), given the synergies that can arise from their combination. However, their joint implementation presents several challenges.
Jaime Macias-Aguayo +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
International Journal of Sustainable Engineering, 2021 In today’s globally competitive market, manufacturing organisations must find innovative ways to delight stakeholders while achieving profitable growth.
Pranay Sureshbhai Parmar +1 more
doaj +1 more source
Jurnal Jaminan Kesehatan Nasional, 2021 Pandemi covid-19 selama tahun 2020 membuat capaian peserta khusus segmen Pekerja Penerima Upah (PPU) mengalami penurunan, khususnya di kantor cabang Jakarta Selatan.Penelitian ini bertujuan untuk mengetahui dampak penerapan metode Lean Six Sigma dalam ...
Teguh Wijaya +3 more
doaj +1 more source
Production planning & control (Print), 2020 This research investigates a possible integration between Lean Six Sigma (LSS) tools and principles and Industry 4.0 technologies. The aim is the development of a new pattern for Operational Excellence through the grounded theory methodology.
A. Chiarini, Maneesh Kumar
semanticscholar +1 more source