Results 81 to 90 of about 299,019 (299)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

POSSIBILITIES OF ORGANIZING THE ROMANIAN MANAGEMENT ACCOUNTING FOR A COMPANY WHICH APPLIES LEAN ACCOUNTING [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
The article presents a way of organizing the management accounting and the calculation of costs for the companies whose management is based on Lean thinking.
OFILEANU DIMI
doaj  

Lean Production: A Way To Reduce The Internal Inventory And Cycle Time

Jurnal Teknik Industri, 2008
The progressive competition among industries and the increase of customer expectation will lead the progressive efforts in reducing the cost of production and logistic activities in the future.
Ilyas Mas'udin
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

How to Use Lean Thinking for the Optimization of Clinical Pathways: A Systematic Review and a Proposed Framework to Analyze Pathways on a System Level. [PDF]

Healthcare (Basel), 2023
Vijverberg JRG, Rouppe van der Voort MBV, van der Nat PB, Mosselman MJ, Rigter S, Biesma DH, van Merode F.   +6 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Instrumento de avaliação para melhorias em processos organizacionais: caso do transporte coletivo rodoviário urbano de Porto Alegre Assessment instrument for organizational process improvement: the case of urban passengers transportation in Porto Alegre

Production, 2007
Este artigo apresenta os dados obtidos a partir de estudos de casos em três empresas de transporte coletivo rodoviário urbano de Porto Alegre, estudos estes realizados no segundo semestre de 2004.
Miriam Borchardt, Miguel Afonso Sellitto, Giancarlo Medeiros Pereira   +2 more
doaj   +1 more source

Research on outpatient capacity planning combining lean thinking and integer linear programming. [PDF]

BMC Med Inform Decis Mak, 2023
Hua L, Dongmei M, Xinyu Y, Xinyue Z, Shutong W, Dongxuan W, Hao P, Ying W.   +7 more
europepmc   +1 more source

Pendekatan Lean Thinking Dengan Menggunakan Mengggunakan Metode Root Cause Analysis Untuk Mengurangi Non Value Added Activities [PDF]

, 2014
Untuk memenangkan persaingan pasar maka supply chain harus menyediakan produk yang murah, berkualitas, tepat waktu, dan bervariasi. Objek penelitian ini merupakan salah satu Perusahaan jasa yang bergerak pada bidang warehousing, forwarding, dan ekspedisi.
Syawalluddin, M. W. (M)
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source