Results 71 to 80 of about 36,022 (270)
Learnability of Quantum Neural Networks
PRX Quantum, 2021 Quantum neural network (QNN), or equivalently, the parameterized quantum circuit (PQC) with a gradient-based classical optimizer, has been broadly applied to many experimental proposals for noisy intermediate-scale quantum (NISQ) devices.
Yuxuan Du +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Online Learning: Beyond Regret [PDF]
, 2011 We study online learnability of a wide class of problems, extending the results of (Rakhlin, Sridharan, Tewari, 2010) to general notions of performance measure well beyond external regret.
Rakhlin, Alexander +2 more
core +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Open LinguisticsThis paper examines vowel harmony in Dagaare using the Tier-Based Strictly Local (TSL) framework, focusing on tongue root, rounding, backness, and height harmonies.
Angsongna Alexander
doaj +1 more source
Usability testing to evaluate user experience on cyclers for automated peritoneal dialysis
Renal Replacement Therapy, 2021 Background In the development of medical devices usability is an important aspect standing alongside performance and safety. Peritoneal dialysis (PD) can be provided by use of automated PD (APD), assisted by a cycler performing the solution exchanges ...
Thore Reitz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
A perspective on doubling constructions in Dutch
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2008 Scope-bearing elements for negations and questions may appear in Dutch child language as “doubling” constructions. The doublings are not part of the adult system. They arise spontaneously in early and later child language.
Jacqueline van Kampen
doaj +1 more source