Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source
Development of an Immersive Virtual Reality-Based Nursing Program Involving Patients with Respiratory Infections. [PDF]
Ji EJ, Lee SS, Lee EK.
europepmc +1 more source
National learner satisfaction survey: adults in FE, apprenticeship, other LR and PCDL (BIS research paper number 17) [PDF]
Klein, Angela +4 more
core
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija +22 more
wiley +1 more source
National learner satisfaction survey: FE learners with learning difficulties and/or disabilities (LDD) (BIS research paper number 22) [PDF]
Klein, Angela +3 more
core
Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu +15 more
wiley +1 more source
Leaning into Necessary Discomforts: Striving for Clinical Excellence While Maintaining Wellness. [PDF]
Patel HH, Lin E.
europepmc +1 more source
National learner satisfaction survey: apprentices report (BIS research paper number 19) [PDF]
Klein, Angela +4 more
core
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Primary teachers' acceptance and sustained adoption of AI powered learner corpora for writing instruction through TAM and ECM perspectives. [PDF]
Zhang N, Wong WL, Barrot J.
europepmc +1 more source

