Results 61 to 70 of about 896 (213)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Kinerja Dosen dan Pengaruhnya dalam Memotivasi Minat Belajar Mahasiswa [PDF]

open access: yes, 2015
This research is about the influence of Lecturer Performance toward Student's Learning Interest. The aim of this research is to find out about is it true that lecture performance influence students learning interest.
Iskandar, F. (Fadil)
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

A Multi-Disciplinary Project to Enhance Workplace Readiness [PDF]

open access: yes, 2015
Engineering graduates are expected to develop a breadth of competencies to prepare for the workplace, encompassing technical knowledge, problem solving and interpersonal skills (IPENZ, 2009). Engineering education often focuses most on the development of
Harris, Trudy
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Compentency of Elementary School Teacher In Written Language Learning [PDF]

open access: yesProceedings of the The 3rd International Conference on Advance & Scientific Innovation, 2020
E Sukma   +4 more
openaire   +1 more source

Sikap Pensyarah Teknologi Pendidikan Terhadap Pengintegrasian E-Pembelajaran Dalam Instruksi Di Institusi Perguruan Di Malaysia [PDF]

open access: yes, 2003
Peranan pendidik guru adalah penting sebagai role-model dan sebagai introducer of the technology kepada guru dan guru-guru pelatih. Oleh itu, sikap pensyarah teknologi pendidikan dapat memberi hala tuju yang positifkepada guru-guru pelatih dalam ...
Mohamad, Faisal
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Institutional reflexivity [PDF]

open access: yes
How can we understand the innovativeness of firms or organizations in general, and how should we assess it in terms of nontechnological innovation? My paper deals with these two questions. The ability of companies to adapt to new circumstances, to create
Moldaschl, Manfred
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Home - About - Disclaimer - Privacy