Results 41 to 50 of about 71,766 (218)

Benchmarking Foot Trajectory Estimation Methods for Mobile Gait Analysis

Sensors, 2017
Mobile gait analysis systems based on inertial sensing on the shoe are applied in a wide range of applications. Especially for medical applications, they can give new insights into motor impairment in, e.g., neurodegenerative disease and help objectify ...
Julius Hannink, Malte Ollenschläger, Felix Kluge, Nils Roth, Jochen Klucken, Bjoern M. Eskofier   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Harmonizing the CBCL and SDQ ADHD scores by using linear equating, kernel equating, item response theory and machine learning methods

Frontiers in Psychology
IntroductionA problem that applied researchers and practitioners often face is the fact that different institutions within research consortia use different scales to evaluate the same construct which makes comparison of the results and pooling ...
Miljan Jović, Maryam Amir Haeri, Andrew Whitehouse, Stéphanie M. van den Berg   +3 more
doaj   +1 more source

Vagus activation by Cold Face Test reduces acute psychosocial stress responses

Scientific Reports, 2022
Chronic stress is linked to dysregulations of the two major stress pathways—the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis, which could for example result from maladaptive responses to repeated acute stress.
Robert Richer, Janis Zenkner, Arne Küderle, Nicolas Rohleder, Bjoern M. Eskofier   +4 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

A Conceptual Framework for Mobile Augmented-Reality Storytelling to Support Collaborative Language Learning in Vocational Education and Training

Multimodal Technologies and Interaction
Augmented Reality (AR) has been found to produce significant effects on individual learning outcomes but its impact on collaborative applications remains moderate.
Eirini Maria Paraskevioti, Athanasios Christopoulos, Stylianos Mystakidis, Mikko-Jussi Laakso, Tapio Salakoski   +4 more
doaj   +1 more source

A Deep Learning Approach to Position Estimation from Channel Impulse Responses

Sensors, 2019
Radio-based locating systems allow for a robust and continuous tracking in industrial environments and are a key enabler for the digitalization of processes in many areas such as production, manufacturing, and warehouse management.
Arne Niitsoo, Thorsten Edelhäußer, Ernst Eberlein, Niels Hadaschik, Christopher Mutschler   +4 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A Hopeful Future? Preparedness and Optimism-Pessimism About the Future of Post-secondary Education

Open Praxis
This study investigates the following research questions in the Canadian and US contexts: 1) To what extent do those working at post-secondary institutions expect the future of post-secondary education to change over the next five years? 2) Do they feel
Nicole Johnson, Jeff Seaman, Julia Seaman   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source