Results 101 to 110 of about 620,156 (317)

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Gamma and beta bursts during working memory readout suggest roles in its volitional control

Nature Communications, 2018
Previously, the authors have shown that working memory can be maintained by brief gamma oscillation bursts. Here, the authors use a new task to further demonstrate the dynamics of gamma and beta oscillations in working memory readout, independent of ...
Mikael Lundqvist, Pawel Herman, Melissa R. Warden, Scott L. Brincat, Earl K. Miller   +4 more
doaj   +1 more source

Bidirectional ocular dominance plasticity of inhibitory networks: recent advances and unresolved questions

Frontiers in Cellular Neuroscience, 2010
Monocular visual deprivation (MD) produces profound changes in the ocular dominance (OD) of neurons in the visual cortex. MD shifts visually evoked responses away from the deprived eye and towards domination by the open eye.
Gordon B Smith, Mark F Bear
doaj   +1 more source

Learning new words: effects of meaning, memory consolidation, and sleep [PDF]

, 2010
Although encountering novel words in one's own language in adulthood is not an uncommon event, the relevant cognitive processes have become the target of systematic investigation only in recent years.
Tamminen, Jakke
core  

Differential involvement of hippocampal calcineurin during learning and reversal learning in a Y-maze task [PDF]

, 2006
The regulation and function of the calcium-dependent phosphatase calcineurin (CaN, protein phosphatase 2B) in learning and memory remain unclear, although recent work indicates that CaN may play a differential role in training and reversal training.
Havekes, Robbert,, Luiten, Paul G. M., Havekes, Robbert, Nijholt, Ingrid M.,, van der Zee, Eddy A., Havekes, Robbert; id_orcid, Nijholt, Ingrid M., Luiten, Paul G.M.,, Zee, Eddy A. van der,   +8 more
core   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cortical organoids

Nature Communications
Human cerebral organoids derived from induced pluripotent stem cells can recapture early developmental processes and reveal changes involving neurodevelopmental disorders. Mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene are associated
Tatsuya Osaki, Chloe Delepine, Yuma Osako, Devorah Kranz, April Levin, Charles Nelson, Michela Fagiolini, Mriganka Sur   +7 more
doaj   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

What associative learning in insects tells us about the evolution of learning and fixed behavior [PDF]

, 2015
Contemporary models for the evolution of learning suggest that environmental predictability plays a critical role in whether learning is expected to evolve in a particular species, a claim originally made over 50 years ago.
Hollis, Karen L., Guillette, Lauren M., Hollis, Karen, Guillette, Lauren   +3 more
core   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source