Results 61 to 70 of about 279,125 (307)

Blended Intensive Programmes - BIP: Students' Motivations and Entrepreneurship Learning Experiences

open access: yesEduSer
This research examines the motivations and entrepreneurship learning experiences, focusing on a business simulation game implemented in a Blended Intensive Program (BIP) developed by a European higher education consortium, Stars EU.
Elaine Scalabrini   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

New Ways to Learn Geography – Challenges of the 21st Century

open access: yesQuaestiones Geographicae, 2018
The aim of the article is to get a closer overview of the non-instructional methods of the teaching-learning process of geography. To achieve this goal, the results of the international project Borderland: Border Landscapes Across Europe (undertaken in ...
Markuszewska Iwona   +2 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Green Subsidies and Learning-by-doing in the Windmill Industry. [PDF]

open access: yes
This paper examines the remarkable learning-by-doing in the windmill industry since it emerged in the beginning of the 1980's. Green subsidies for producing electricity by wind power has been a precondition for the rapid growth in the production of ...
Erik Strøjer Madsen   +2 more
core  

Knowledge Transfer as a Leverage of Change, the Case of the Public Prosecutor Office of Naples

open access: yesInternational Journal for Court Administration, 2013
The public prosecutor’s office of Naples is the biggest prosecutorial institution in Italy. Because of its size,  its visibility, and its location in Naples, the PPO it is an  interesting and difficult case from an organization development perspective ...
Daniela Piana
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Organizational Capital, Learning-by-Doing and Investment Volatility [PDF]

open access: yes
This paper addresses the issue of plant-level investment volatility in the context of a purely convex model, where fluctuations are driven by technological shocks.
Fabiano Rodrigues Bastos
core  

Using Theories of Change to inform implementation of health systems research and innovation: experiences of Future Health Systems consortium partners in Bangladesh, India and Uganda

open access: yesHealth Research Policy and Systems, 2017
Background The Theory of Change (ToC) is a management and evaluation tool supporting critical thinking in the design, implementation and evaluation of development programmes.
Ligia Paina   +10 more
doaj   +1 more source

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