Results 31 to 40 of about 81,419 (266)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Education Capitalization and Learning Accesstability

Fikroh: Jurnal Pemikiran dan Pendidikan Islam, 2021
Education has a much needed role for everyone to give new knowledge.  Education requires materials that support it to be well-maintained. In accordance with the opening of the Contstitution 1945 is educate the life of the nation.  Lately, education is used as a new tool to gain profit from all aspects in other words of the commercialization of ...
Abdul Muhid, Idham Okalaksana Putra
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comorbid Anxiety and Depression and Related Factors Among Pregnant and Postpartum Chinese Women During the Coronavirus Disease 2019 Pandemic

Frontiers in Psychology, 2021
Objective: To identify the prevalence of comorbid anxiety and depression (CAD) and analyze the relationship between CAD and sociodemographic and obstetric-related variables in pregnant and postpartum Chinese women during the COVID-19 pandemic.Methods ...
Zheng Luo, Luyao Xue, Li Ma, Zhengkui Liu, Zhengkui Liu   +4 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Role of Creativity in the Effectiveness of Cognitive Reappraisal

Frontiers in Psychology, 2017
As a well-recognized and widely adopted emotional regulation strategy, cognitive reappraisal has generally been proven to be efficient. However, the cognitive mechanism underlying regulatory efficiency, particularly the role of creativity, in cognitive ...
Xiaofei Wu, Tingting Guo, Tengteng Tang, Baoguo Shi, Jing Luo, Jing Luo   +5 more
doaj   +1 more source

Social capital, capital goods, and the production of learning

The Journal of Socio-Economics, 2000
The concept of social capital, according to James Coleman (1990), blurs distinctions between types of social structures. Most researchers who embrace Coleman's concept choose to preserve its broad content rather than sharpen its analytic bite. In order to further develop social capital as a theory capable of explanation, the analytic contribution of ...
openaire   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Dynamic reconfiguration of default and frontoparietal network supports creative incubation

NeuroImage
Although creative ideas often emerge during distraction activities unrelated to the creative task, empirical research has yet to reveal the underlying neurocognitive mechanism. Using an incubation paradigm, we temporarily disengaged participants from the
Ziyi Li, Ze Zhang, Tengteng Tan, Jing Luo   +3 more
doaj   +1 more source