Results 81 to 90 of about 14,721,985 (357)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The impact of digital educational games on student’s motivation for learning: The mediating effect of learning engagement and the moderating effect of the digital environment

PLoS ONE
The utilization of digital educational infrastructure in schools has propelled digital educational games to the forefront of educational innovation.
Youling Li, Di Chen, Xinxia Deng
semanticscholar   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Just in case: undergraduate students identifying and mitigating barriers to their sexual and reproductive health needs

BMC Women's Health
Background Many U.S. colleges and universities offer access to a healthcare center that provides sexual and reproductive health (SRH) resources, services, and products.
Rachel Olson, Jonathan Lehman, Angie Mejia, Rachael Ojeikhodion, Kristin Osiecki, Emily Kathambi, Silas Swarnakanth Kati, Anita Randolph   +7 more
doaj   +1 more source

How peer relationships affect academic achievement among junior high school students: The chain mediating roles of learning motivation and learning engagement

BMC Psychology
Background Despite the recognition of the impact of peer relationships, learning motivation, and learning engagement on academic achievement, there is still a gap in understanding the specific mechanisms through which peer relationships impact academic ...
Yanhong Shao, Shu-Min Kang, Quan Lu, Chao Zhang, Ruoxi Li   +4 more
semanticscholar   +1 more source

M-learning and student engagement: Factors that support students' engagement in m-learning [PDF]

, 2011
Mobile learning (m-learning) is learning that takes place in a variety of contexts, within and beyond traditional learning environments, utilising any type of mobile device.
Martin, Romana
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Addressing mental health deserts: a geographic and economic analysis of mental health service gaps in Houston

Frontiers in Public Health
IntroductionThe increasing prevalence of mental health challenges in the United States, particularly among low-income communities, has highlighted significant disparities in access to mental health services. This study investigated the concept of “mental
Damien Kelly, Chakema Carmack, Chakema Carmack   +2 more
doaj   +1 more source

Students' digital technology attitude, literacy and self-efficacy and their effect on online learning engagement

International Journal of Educational Technology in Higher Education
This study utilised students' online engagement, digital technology attitude, digital literacy, and self-efficacy theories to develop and test a model connecting these factors within a regional university in Australia.
S. Getenet, R. Cantle, P. Redmond, P. Albion   +3 more
semanticscholar   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source