Results 51 to 60 of about 501,647 (314)

The learning organization as a context for value co-creation [PDF]

open access: yes, 2019
Purpose This paper aims to explore the relationship between the concept of the learning organization and that of the co-creation of value. Design/methodology/approach The paper is conceptual in nature and draws on data from a case study of a small ...
Chew, E, Mastio, E, Dovey, KA
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Relationship between Leadership and Characteristics of Learning Organizations in Deployed Military Units: An Exploratory Study

open access: yesAdministrative Sciences, 2013
Previous research has shown that military units operating in the context of risky missions display the characteristics of a Learning Organization.
Eileen Van Aken   +3 more
doaj   +1 more source

Review of Learning City Indicators in the areas of Yazd city [PDF]

open access: yesکاوش‌های جغرافیایی مناطق بیابانی, 2021
Introduction: Learning and the learning process (interactions between the learner and the social environment) is one of the topics for the development and excellence of today's urban communities.Globalization and economics, the growth of information ...
mohammadhossein saraei   +1 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

How to Maintain Education During Wars? An Integrative Approach to Ensure the Right to Education

open access: yesOpen Praxis
It is widely acknowledged that the relationship between education, security, and stability is bidirectional. In times of war, access to quality education becomes compromised, and conversely, the absence of proper education constrains individuals to a ...
Soheil Salha   +7 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Diverging assessments of learning organizations during reform implementation [PDF]

open access: yes, 2018
Purpose: This study aims to explore whether hierarchical position and organizational size affect perceptions of a learning organization (LO) during reform implementation.
Borge, Baard H.   +4 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Organizational learning and unlearning capabilities for resilience during COVID-19

open access: yes, 2021
Purpose - The purpose of this paper is to empirically validate the positive effect of learning on organizational resilience and, within this relationship, understand the role of unlearning in the COVID-19 crisis context and progress the current knowledge
Orth, Daniel,, Schuldis, Philipa Maria,
core   +1 more source

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