Results 61 to 70 of about 444,221 (267)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lifelong Learning in Nursing: Perceptions and Realities
Today, where the information is constantly renewed, nothing is stable and change is the keyword, reasons such as the continuousness and speed of change, globalization, informational economy, competition between national economies, unemployment, personal
Emine ŞENYUVA
doaj
The ability to learn from feedback and its impact on the perception of learning
The study described in this article is part of the PhD research work “Model to develop the ability to learn from feedback and improvement in the performance of students in higher education in Guatemala”, conducted in a private university in Guatemala. It
Nidia Giorgis
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh cara belajar dan lingkungan keluarga terhadap hasil belajar mata pelajaran ekonomi kompetensi dasar akuntansi siswa kelas XI IPS di SMA AL-IRSYAD PEKALONGAN baik secara simultan maupun secara ...
Muhammad Yusron
doaj
PENGARUH PENGGUNAAN MEDIA KOMIK DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR MATEMATIKA SISWA SMP
This research is a quasi-experimental research with an experimental design aimed at: 1) know the influence of the presentation of material in the form of comic media and without comic media on student mathematics learning outcomes; 2) know the ...
Widya Putri Ramadhani
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Penelitian ini bertujuan untukmeningkatkan aktivitas belajar siswa dengan menggunakan metode group investigation (GI) pada pokok bahasan pasar pada penelitian ini menggunakan penelitian tindakan kelas (PTK).
Mutthofiyah Mutthofiyah
doaj

