Results 41 to 50 of about 1,010,511 (312)

Modification of the Conventional Influenza Epidemic Models Using Environmental Parameters in Iran [PDF]

open access: yesHealthcare Informatics Research, 2019
ObjectivesThe association between the spread of infectious diseases and climate parameters has been widely studied in recent decades. In this paper, we formulate, exploit, and compare three variations of the susceptible-infected-recovered (SIR) model ...
Ahmad Naserpor   +5 more
doaj   +1 more source

Fitting and Cross-Validating Cox Models to Censored Big Data With Missing Values Using Extensions of Partial Least Squares Regression Models

open access: yesFrontiers in Big Data, 2021
Fitting Cox models in a big data context -on a massive scale in terms of volume, intensity, and complexity exceeding the capacity of usual analytic tools-is often challenging. If some data are missing, it is even more difficult.
Frédéric Bertrand    +3 more
doaj   +1 more source

Reduced-rank Analysis of the Total Least Squares [PDF]

open access: yes2019 IEEE 20th International Workshop on Signal Processing Advances in Wireless Communications (SPAWC), 2019
The reduced-rank method exploits the distortion-variance tradeoff to yield superior solutions for classic problems in statistical signal processing such as parameter estimation and filtering. The central idea is to reduce the variance of the solution at the expense of introducing a little distortion.
Kyatsandra G. Nagananda   +1 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Corticomuscular Activity Modeling by Combining Partial Least Squares and Canonical Correlation Analysis

open access: yesJournal of Applied Mathematics, 2013
Corticomuscular activity modeling based on multiple data sets such as electroencephalography (EEG) and electromyography (EMG) signals provides a useful tool for understanding human motor control systems. In this paper, we propose modeling corticomuscular
Xun Chen   +3 more
doaj   +1 more source

New Constructed EEM Spectra Combined with N-PLS Analysis Approach as an Effective Way to Determine Multiple Target Compounds in Complex Samples

open access: yesMolecules, 2022
Excitation–emission matrix (EEM) fluorescence spectroscopy has been applied to many fields. In this study, a simple method was proposed to obtain the new constructed three-dimensional (3D) EEM spectra based on the original EEM spectra.
Zeying Li   +5 more
doaj   +1 more source

High-performance numerical algorithms and software for structured total least squares

open access: yes, 2005
We present a software package for structured total least squares approximation problems. The allowed structures in the data matrix are block-Toeplitz, block-Hankel, unstructured, and exact.
Van Huffel, S.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Robust Total Least Squares Estimation Method for Uncertain Linear Regression Model

open access: yesMathematics, 2023
In data analysis and modeling, least squares and total least squares are both mathematical optimization techniques. It is noteworthy that both the least squares method and the total least squares method are used to deal with precise and random data ...
Hongmei Shi   +4 more
doaj   +1 more source

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