Results 171 to 180 of about 265,644 (356)

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

open access: yesEuropean Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg   +17 more
wiley   +1 more source

Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The synthesis of triterpenoid saponins bearing a Lewis‐X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin‐targeted therapeutic applications, are prepared through iterative and ...
Oscar Javier Gamboa Marin   +3 more
wiley   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

open access: yesExploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu   +4 more
wiley   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

open access: yesFood Frontiers, EarlyView.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah   +1 more
wiley   +1 more source

An inclusive insight on dietary resistant protein and protein hydrolysates: Structural intricacy, bioactivity and benefits on human health

open access: yesFood Biomacromolecules, EarlyView.
Abstract This assessment explores the health benefits of resistant proteins and protein hydrolysates in human nutrition, highlighting their bioactive properties and amino acid compositions. Resistant proteins, which withstand digestion and operate comparably to dietary fibre and protein hydrolysates, obtained from enzymatic breakdown of proteins ...
Mohan Das   +7 more
wiley   +1 more source

Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma. [PDF]

open access: yesSci Rep
Tsukamoto S   +9 more
europepmc   +1 more source

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