Results 271 to 280 of about 229,497 (351)

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre   +3 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Help from the past to cope with the future: Vitis sylvestris as a resource for abiotic stress resilience

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Viticulture is facing increasing challenges due to climate change. The focus on fast growth and sweet berries has come at the expense of stress resilience. Grafting onto Phylloxera‐resistant rootstocks from American species has been the most successful form of ecological pest management.
Samia Daldoul   +6 more
wiley   +1 more source

Altered Glycosylation of PSA in Prostate Cancer Tissue

open access: yesThe Prostate, EarlyView.
ABSTRACT Background The glycosylation of proteins is commonly altered in cancer. This offers novel opportunities for cancer biomarker development. As prostate‐specific antigen (PSA) is a glycoprotein, identification of cancer‐specific PSA‐glycoforms is feasible. Such PSA‐glycoforms may provide valuable diagnostic and prognostic information. Methods PSA‐
Hannu Koistinen   +7 more
wiley   +1 more source

Potential roles of antibodies with different classes in IgG4‐related diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li   +6 more
wiley   +1 more source

Low‐Background His‐Tag‐Targeting Probes for Turn‐On Fluorescence Detection of Cell Surface Proteins and Their Binding Interactions

open access: yesSmall, EarlyView.
Conjugating a tri‐nitrilotriacetic acid unit to quinoline‐based cyanine dyes generated probes that fluoresce upon binding to His‐tagged proteins on cell surfaces. Using the thiazole orange‐bearing probe, the binding of the receptor binding domain (RBD) of the SARS‐CoV‐2 virus to host cells is readily detected, enabling the straightforward ...
Pragati Kishore Prasad   +18 more
wiley   +1 more source

Interparticle Crosslinked Ion‐Responsive Microgels for 3D and 4D (Bio)Printing Applications

open access: yesSmall, EarlyView.
A novel strategy is developed that enables interparticle crosslinking of microgels, eliminating the need for filler hydrogels and preserving essential microscale void spaces to support cell migration and vascularization. These microgels possesses unique, ion‐responsive shrinking behavior primarily by the Hofmeister effect, reversible upon the removal ...
Vaibhav Pal   +8 more
wiley   +1 more source

Tumor‐Targeted Radioiodinated Glyconanoparticles for Doxorubicin Delivery and Auger‐Chemotherapy in Triple‐Negative Breast Cancer

open access: yesSmall, EarlyView.
Combining multiple anti‐tumor therapeutic modalities using nanoparticles allows harnessing their therapeutic potential in combination with minimal side effects at lower doses. This study focuses on the development of tumor‐responsive core‐shell glyconanoparticle formulation targeting galectin‐3 in triple‐negative breast cancer (TNBC) for Auger ...
Shishu Kant Suman   +3 more
wiley   +1 more source

Multi‐Functional Polydopamine‐Mucin Hollow Particles Provide Tunable Shell Permeability, ROS Scavenging, Tissue Adhesion, and Lubricity for Biomedical Applications

open access: yesSmall, EarlyView.
This study presents a facile method to fabricate hollow, multifunctional polydopamine (PDA)‐mucin microparticles. The permeability of the particle shells can be tuned by adding ionic or molecular “locks”, so that cargo molecules can be trapped within the shells with high encapsulation efficiency.
Di Fan   +6 more
wiley   +1 more source

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