Results 271 to 280 of about 265,644 (356)

Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study

Aging Cell, EarlyView.
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi, Hang‐Mao Lee, Dan Liu, Marc D. Beyer, Paolo Salomoni, Monique M. B. Breteler, N. Ahmad Aziz   +6 more
wiley   +1 more source

Biochemical analysis of Caenorhabditis elegans surface mutants [PDF]

, 1997
Blaxter, M.L., Link, C., Silverman, M.
core  

Aging Compromises Terminal Differentiation Program of Cytotoxic Effector Lineage and Promotes Exhaustion in CD8+ T Cells Responding to Coronavirus Infection

Aging Cell, EarlyView.
In a MHV infection model with age‐associated increased mortality, we demonstrate that aging impairs, instead of promoting, the terminal differentiation program of virus‐specific CD8+ T cells through downregulating key transcriptional regulators of terminal differentiation.
Ziang Zhu, Guohua Lou, Ying Luo, Kiddist Yihunie, Jonathan Hoar, Juan A. Daniel, Bret M. Evers, Chen Yao, Tuoqi Wu   +8 more
wiley   +1 more source

Associations of serum sLOX-1 levels with disease severity and 3-month function prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study. [PDF]

Front Neurol
Ye X, He H, Song H, Huang J, Zhang Z, Zhou Y.   +5 more
europepmc   +1 more source

Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats

Aging Cell, EarlyView.
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura, Csaba Kerepesi, Juliet Polok Sarkar, Ferenc Torma, Zoltan Bori, Lei Zhou, Peter Bakonyi, Attila Kolonics, Laszlo Balogh, Mitsuru Higuchi, Vivien Pillár, Karolina Pircs, Lauren Gerard Koch, Steven Loyal Britton, Erika Koltai, Zsolt Radak   +15 more
wiley   +1 more source

Characterization of HOL-30: a novel tandem-repeat galectin from the marine sponge <i>Halichondria okadai</i>. [PDF]

BBA Adv
Ohkawa M, Kamata K, Kawsar SMA, Gerdol M, Fujii Y, Ozeki Y.   +5 more
europepmc   +1 more source

Vaccine‐Induced Anti‐IgE Antibodies Neutralize Free IgE but Fail to Bind and Activate Mast Cell‐Displayed IgE

Allergy, EarlyView.
We investigated the mechanisms by which a previously established VLP‐based anti‐IgE vaccine protects against allergic anaphylaxis. We show that passively administered vaccine‐induced IgGs into allergic mice protects them from anaphylaxis without side effects.
Zahra Gharailoo, Monique Vogel, Paul Engeroff, Martin F. Bachmann   +3 more
wiley   +1 more source

Stigmurin encapsulated PLA-PEG ameliorates its therapeutic potential, antimicrobial and antiproliferative activities. [PDF]

Discov Nano
Thakur A, Alajangi HK, Sharma A, Hwang E, Khajuria A, Kumari L, Jaiswal PK, Lim YB, Singh G, Barnwal RP.   +9 more
europepmc   +1 more source

Gastrointestinal Barrier Disruption in Post‐COVID Syndrome Fatigue Patients

Allergy, EarlyView.
Gastrointestinal (GI) barrier disruption in the context of SARS‐CoV‐2 infection is associated with the development of Post‐COVID Syndrome (PCS) Fatigue. Pre‐existing GI complaints may predispose to fatigue development. Monitoring GI symptoms and markers before, during, and after SARS‐CoV‐2 infection is crucial for identifying predictive clinical ...
Johanna Rohrhofer, Viktoria Wolflehner, Johannes Schweighardt, Larissa Koidl, Michael Stingl, Sonja Zehetmayer, Joana Séneca, Petra Pjevac, Eva Untersmayr   +8 more
wiley   +1 more source