Results 281 to 290 of about 352,824 (358)

Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis

Andrology, EarlyView.
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz, Takahiro Yamanaka, Shahrina Akter, Masanori Koyago, Masayuki Shimada   +4 more
wiley   +1 more source

C-reactive protein dissociation drives choroidal neovascularization in age-related macular degeneration. [PDF]

Sci Rep
Hernandez M, Romero-Vázquez S, Recalde S, Bezunartea J, Orduña MM, Belza-Zuazu I, García-Layana A, Adán A, Fernández-Robredo P, Molins B.   +9 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Effects of Catfish Egg Lectin on Cancer Cells Differ According to the Globotriaosylceramide Species They Express. [PDF]

Int J Mol Sci
Sugawara S, Kikuchi K, Tatsuta T, Fujimura T, Hosono M.   +4 more
europepmc   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

Brain Pathology, EarlyView.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau, Rebecca Crisp, Mallory Keating, Elizabeth Ochoa, Timothy E. Richardson, Margaret E. Flanagan, Jamie M. Walker, Sarah C. Hopp, Kevin F. Bieniek   +8 more
wiley   +1 more source

Lanthanum exposure and its metabolomic effects on Ruditapes philippinarum. [PDF]

Sci Rep
Mastrorocco F, Guglielmi MV, De Martino L, Musicco C, Cox SN, Pesole G, Scillitani G, Leoni C.   +7 more
europepmc   +1 more source

Comprehensive Colorectal Cancer Stem Cell Transcriptomic Signatures That Can Predict Patient Prognostic Outcomes

Cancer Science, EarlyView.
We characterized colorectal cancer stem‐like cell (CRC‐SC)–derived transcriptomic subtypes based on mRNA expression of 57 patient‐derived SC lines. Expression profiles were compared with normal colonic epithelium stem‐like cells (NCE‐SCs), yielding differentially expressed genes.
Fumihiko Kakizaki, Hiroyuki Miyoshi, Takehito Yamamoto, Tomonori Morimoto, Hiroyuki Matsubara, Shoichi Kitano, Tadayoshi Yamaura, Hisatsugu Maekawa, J. B. Brown, Tosiya Shun Sato, Kazutaka Obama, Yoshiharu Sakai, Kenji Kawada, Makoto Mark Taketo   +13 more
wiley   +1 more source

Biochemical Applications of Microbial Rare Glycan Biosynthesis, Recognition, and Sequencing. [PDF]

Biochemistry
Joo J, Koid A, Kim H, Ghosh A, Lee S, Sheshova M, Lupoli TJ.   +6 more
europepmc   +1 more source