Results 31 to 40 of about 265,644 (356)

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

Frontiers in Cellular and Infection Microbiology, 2022
Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved for HTNV and other hantavirus infections.
Yajing Zhao, Yajing Zhao, Ningbo Zhao, Ningbo Zhao, Yanxing Cai, Yanxing Cai, Hui Zhang, Jia Li, Jiaqi Liu, Chuantao Ye, Yuan Wang, Yamei Dang, Wanying Li, Wanying Li, He Liu, Lianqing Zhang, Yuexiang Li, Liang Zhang, Linfeng Cheng, Yangchao Dong, Zhikai Xu, Yingfeng Lei, Lu Lu, Yingjuan Wang, Wei Ye, Fanglin Zhang   +25 more
doaj   +1 more source

Lectin microarray [PDF]

PROTEOMICS – Clinical Applications, 2009
AbstractLectin microarray is a new technology that utilizes a panel of lectins immobilized on well‐defined substrate for high‐throughout analysis of glycans and glycoproteins. In this article, we have reviewed the fabrication and detection schemes in lectin microarray and discussed its novel applications in glycomics. We have also demonstrated a lectin
Shen, Hu, David T, Wong
openaire   +2 more sources

Functional Recombinants Designed from a Fetuin/Asialofetuin-Specific Marine Algal Lectin, Rhodobindin

Marine Drugs, 2015
Plant lectins have attracted much attention for biomedical applications including targeted drug delivery system and therapy against tumors and microbial infections.
Jong Won Han, Min Gui Jung, Eun Young Shim, Jun Bo Shim, Young Min Kim, Gwang Hoon Kim   +5 more
doaj   +1 more source

Bacterial Lectin FimH and Its Aggregation Hot-Spots: An Alternative Strategy against Uropathogenic Escherichia coli

Pharmaceutics, 2023
Type I fimbriae are the main adhesive organelles of uropathogenic Escherichia coli (UPEC), consisting of four different subunits. Their component with the most important role in establishing bacterial infections is the FimH adhesin located at the ...
Georgia I. Nasi, Konstantina I. Georgakopoulou, Marilena K. Theodoropoulou, Nikos C. Papandreou, Evangelia D. Chrysina, Paraskevi L. Tsiolaki, Vassiliki A. Iconomidou   +6 more
doaj   +1 more source

Structural and biochemical characterization of a new type of lectin isolated from carp eggs. [PDF]

, 2003
A previously unidentified glycoprotein present in the eggs of the carp (Cyprinus carpio) was isolated and structurally characterized. The protein binds to a Sepharose 4B matrix and can be eluted with 0.4 M N-acetylglucosamine. The protein has an apparent
AMORESANO, ANGELA, CAMPAGNOLI M, CASBARRA A, CAUCI M, GALLIANO M, MINCHIOTTI L, PERDUCA M, PUCCI, PIETRO, SALA A, VISAI L   +9 more
core   +1 more source

Distribution of glycan motifs at the surface of midgut cells in the cotton leafworm (Spodoptera littoralis) demonstrated by lectin binding [PDF]

, 2017
Glycans are involved in many biological phenomena, including signal transduction, cell adhesion, immune response or differentiation. Although a few papers have reported on the role of glycans in the development and proper functioning of the insect midgut,
Els J. M. Van Damme, Guy Smagghe, Kaat Cappelle, Kristof De Schutter, Tomasz Walski, Tomasz Walski   +5 more
core   +2 more sources

The complement binding-like domains of the murine homing receptor facilitate lectin activity. [PDF]

, 1991
The leukocyte homing receptor (HR), the endothelial leukocyte adhesion molecule, and gmp140/platelet activation-dependent granule membrane protein are members of a family of adhesion molecules, termed the lectin cell adhesion molecules (LEC-CAMS) which ...
Fennie, C, Geoffrey, J, Imai, Y, Lasky, LA, Rosen, SD, Singer, M, Watson, SR   +6 more
core  

Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]

, 2020
BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G, Lai, D-H, Li, F-J, Lun, Z-R, Xu, Z-S   +4 more
core   +2 more sources

A Lactose-Binding Lectin from the Marine Sponge Cinachyrella Apion (Cal) Induces Cell Death in Human Cervical Adenocarcinoma Cells

Marine Drugs, 2012
Cancer represents a set of more than 100 diseases, including malignant tumors from different locations. Strategies inducing differentiation have had limited success in the treatment of established cancers.
Adriana Uchoa, Ana Heloneida Morais, Hugo Rocha, Adeliana Oliveira, Ruth Oliveira, Paula Santos, Raphael Serquiz, Norberto Monteiro, Luciana Rabelo, Elizeu Santos   +9 more
doaj   +1 more source

Urtica dioica Agglutinin Prevents Rabies Virus Infection in a Muscle Explant Model

Pharmaceutics, 2023
Infection with the rabies virus (RABV) results in a 100% lethal neurological disease once symptoms develop. Post-exposure prophylaxis (PEP) consists of a combination of vaccination and anti-rabies immunoglobulins (RIGs); it is 100% effective if ...
Xinyu Wang, Lisanne Terrie, Guanghui Wu, Els J. M. Van Damme, Lieven Thorrez, Anthony R. Fooks, Ashley C. Banyard, Dirk Jochmans, Johan Neyts   +8 more
doaj   +1 more source