Results 61 to 70 of about 324,815 (204)

Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Urtica dioica agglutinin (UDA) is a carbohydrate-binding small monomeric protein isolated from stinging nettle rhizomes. It inhibits replication of a broad range of viruses, including coronaviruses, in multiple cell types, with appealing selectivity.
Emiel Vanhulle   +10 more
doaj   +1 more source

Beyond the fuzzy lock-and-key: spontaneous symmetry shifts and glycan/lectin logic gates [PDF]

open access: yes, 2012
Changes in the molecular topology of glycan/lectin interaction may explain observed reaction punctuation driven by experimental gradients in reactant concentration. Adoption of a 'biological renormalization' perspective from statistical physics
Rodrick Wallace
core   +1 more source

Lectin based glycoprotein analysis [PDF]

open access: yes, 2008
Many of the biopharmaceutical therapeutics entering the market and currently in clinical trails are recombinant glycoprotein molecules, the glycan moieties of which have a significant impact on efficacy and immunogenicity.
Clarke, Paul A.   +4 more
core  

Survival outcome and EMT suppression mediated by a lectin domain interaction of Endo180 and CD147 [PDF]

open access: yes, 2014
Epithelial cell-cell contacts maintain normal glandular tissue homeostasis, and their breakage can trigger epithelial-to-mesenchymal transition (EMT), a fundamental step in the development of metastatic cancer.
Darby, Steven   +8 more
core   +2 more sources

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

open access: yesJournal of Fungi, 2020
Mushrooms have been valued as food and health supplements by humans for centuries. They are rich in dietary fiber, essential amino acids, minerals, and many bioactive compounds, especially those related to human immune system functions. Mushrooms contain
Shuang Zhao   +6 more
doaj   +1 more source

Natural lectin activity in the haemolymph of Panstrogylus megistus (Heteroptera: Reduvidae) Atividade lectínica na hemolinfa de Panstrongylus megistus (Heteroptera: Reduviidae)

open access: yesMemorias do Instituto Oswaldo Cruz, 1988
The haemolymph of Panstrongylus megistus showed a natural lectin activity for a wide range of vertebrate erythocytes. Agglutination was observed against all vertebrate erythrocytes tested (human ABO, duck, rabbit, mouse, sheep, chicken and cow).
Y. M. Gomes   +2 more
doaj   +1 more source

Overexpression of Nictaba-like lectin genes from glycine max confers tolerance towards Pseudomonas syringae infection, aphid infestation and salt stress in transgenic Arabidopsis plants [PDF]

open access: yes, 2016
Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Smagghe, Guy   +2 more
core   +3 more sources

Sense–Analyze–Respond–Actuate (SARA) Paradigm: Proof of Concept System Spanning Nanoscale and Macroscale Actuation for Detection of Escherichia coli in Aqueous Media

open access: yesActuators, 2020
Foodborne pathogens are a major concern for public health. We demonstrate for the first time a partially automated sensing system for rapid (~17 min), label-free impedimetric detection of Escherichia coli spp.
Cassie A. Giacobassi   +7 more
doaj   +1 more source

High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]

open access: yes, 2011
Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Ahmed   +54 more
core   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

open access: yes, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H.   +4 more
core   +1 more source

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