Mannose-binding lectin binds IgM to activate the lectin complement pathway in vitro and in vivo
Immunobiology, 2006 Recent evidence has implicated a role for the MBL-dependent lectin pathway in gastrointestinal and myocardial ischemia/reperfusion (I/R)-induced injury. However, previous studies have implicated IgM and the classical pathway as initiators of complement activation following I/R. Thus, we investigated the potential interaction between MBL and IgM leading
Kazue Takahashi +5 more
openaire +4 more sources
Cancer Communications, EarlyView.Abstract Background Third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) show initial efficacy in EGFR‐mutated lung cancer, but residual disease persists. This study aimed to investigate cluster of differentiation 24 (CD24) as a translational immunotherapeutic target for enhancing third‐generation EGFR‐TKI efficacy.
Jiaqi Liang +16 more
wiley +1 more source
Protein Phosphatase 2A, a Negative Regulator of the ERK Signaling Pathway, Is Activated by Tyrosine Phosphorylation of Putative HLA Class II-associated Protein I (PHAPI)/pp32 in Response to the Antiproliferative Lectin, Jacalin [PDF]
, 2004 Lu‐Gang Yu +4 more
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Chemistry &Biodiversity, EarlyView.Chemical profile, photoprotective, and antioxidant potential of Padina sp., Caulerpa sertularioides, and Solieria filiformis collected in Bahia, Brazil. ABSTRACT Seaweeds have wide biotechnological applications. This study evaluated the chemical profile, photoprotective, and antioxidant potential of Padina sp., Caulerpa sertularioides, and Solieria ...
Keila Almeida Santana +8 more
wiley +1 more source
L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement [PDF]
, 2004 Nicholas J. Lynch +8 more
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C‐6‐Modified 2‐F‐Fucose Derivatives as Inhibitors of Fucosyltransferases
ChemBioChem, EarlyView.A series of C6‐modified guanosine‐diphosphate‐2‐F‐fucose analogs and corresponding prodrugs are designed, synthesized, and biologically evaluated as inhibitors of cellular fucosylation. Certain analogs potently inhibit fucosyltransferases (FUT) FUT1, 3, 6, and 9 while showing minimal activity for FUT8, highlighting the potential for selective FUT ...
Yanyan Liu, Geert‐Jan Boons
wiley +1 more source
Platelets and the Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus or Antiphospholipid Syndrome. [PDF]
TH Open, 2023 Vils SR, Troldborg A, Hvas AM, Thiel S.
europepmc +1 more source
Preoperative Mannan‐Binding Lectin Pathway and Prognosis in Colorectal Cancer [PDF]
, 2004 Henriette Ytting +4 more
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Cereal Chemistry, EarlyView.ABSTRACT Background and Objectives This study evaluated the effect of seed shape on the composition, functional, and quality properties of pea flours and protein isolates. Wrinkled‐seed (WPAs) and round‐seed (RPA) pea accessions were selected from a genome‐wide association study panel.
Cassia Galves +4 more
wiley +1 more source
Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins [PDF]
, 2005 Neil C. Rogers +10 more
openalex +1 more source