Results 141 to 150 of about 104,017 (255)

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Lectin pathway components and autoantibodies as novel immunological biomarkers in systemic lupus erythematosus (SLE) patients from Western India. [PDF]

Sci Rep
Rai K, Khatri R, Jose A, Konkar H, Nadkar M, Rajadhyaksha A, Roumenina L, Parande A, Bitla G, Padwal V, Madkaikar M, Pradhan V.   +11 more
europepmc   +1 more source

The role of the lectin pathway of the complement system in SARS-CoV-2 lung injury. [PDF]

Transl Res, 2021
Malaquias MAS, Gadotti AC, Motta-Junior JDS, Martins APC, Azevedo MLV, Benevides APK, Cézar-Neto P, Panini do Carmo LA, Zeni RC, Raboni SM, Fonseca AS, Machado-Souza C, Moreno-Amaral AN, de Noronha L.   +13 more
europepmc   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Activation of the Complement/Lectin Pathway, Angiopoietin/Tie-2/VEGF-System, Cytokines and Chemokines in Different Angioedema Subtypes. [PDF]

Eur J Immunol
Duda KM, Gehring M, Wedi B.
europepmc   +1 more source

Brain death-induced lung injury is complement dependent, with a primary role for the classical/lectin pathway. [PDF]

Am J Transplant, 2021
van Zanden JE, Jager NM, Seelen MA, Daha MR, Veldhuis ZJ, Leuvenink HGD, Erasmus ME.   +6 more
europepmc   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Guianensin, a Blackfly Salivary Protein, Inhibits the Lectin Pathway of Complement. [PDF]

J Med Chem
Valenzuela Leon PC, Ring ME, Nishiduka E, Bonilla B, Cruz P, Martinez EP, Percopo C, Calvo E.   +7 more
europepmc   +1 more source

Components of the Lectin Pathway of Complement in Haematologic Malignancies. [PDF]

Cancers (Basel), 2020
Cedzyński M, Świerzko AS.
europepmc   +1 more source

Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression. [PDF]

Nat Cancer, 2021
Magrini E, Di Marco S, Mapelli SN, Perucchini C, Pasqualini F, Donato A, Guevara Lopez ML, Carriero R, Ponzetta A, Colombo P, Cananzi F, Supino D, Reis ES, Peano C, Inforzato A, Jaillon S, Doni A, Lambris JD, Mantovani A, Garlanda C.   +19 more
europepmc   +1 more source