Results 321 to 330 of about 2,513,226 (377)

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review

Journal of Periodontal Research, EarlyView.
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana, Giacomo Baima, Giovanni Iaderosa, Francesco Franco, Jianjian Zhang, Giovanni Nicolao Berta, Federica Romano, Mario Aimetti   +7 more
wiley   +1 more source

Sexual Selection on Non‐Ornamental Traits Is Underpinned by Evidence of Genetic Constraints on Sex‐Biased Expression in Dusky Pipefish

Molecular Ecology, EarlyView.
ABSTRACT Species lacking distinct secondary sex characteristics, such as differences in size or morphology, are often thought to experience lower levels of sex‐specific selection in comparison to highly sexually dimorphic organisms. However, monomorphism in classic visible traits could be a result of genetic or physiological constraints that prevent ...
Nicole M. Tosto, Emily Rose, Heather D. Mason, Judith E. Mank, Sarah P. Flanagan   +4 more
wiley   +1 more source

Mechanisms governing bacterial capsular polysaccharide attachment and chain length

Annals of the New York Academy of Sciences, EarlyView.
Abstract Capsular polysaccharides (CPSs) are high‐molecular weight glycopolymers that form a capsule layer on the surface of many bacterial species. This layer serves as a crucial barrier between bacteria and their environment, protecting them from host immune responses and environmental stressors while facilitating adaptation to host niches.
Saroj Khadka, Emily L. Kinney, Brooke E. Ryan, Laura A. Mike   +3 more
wiley   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Plant‐derived vesicle‐like nanoparticles in food crops: emerging insights into nutritional biofortification and biomedical applications

Plant Biotechnology Journal, EarlyView.
Summary Food crops, as the cornerstone of human nutrition, not only provide essential macronutrients but also encompass a rich spectrum of bioactive compounds that promote health. Of particular significance are underutilized minor crops, which contain unique beneficial components with proven nutraceutical properties. These valuable bioactive components
Jie Wang, Zhaosheng Kong
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

A novel approach to enhance resistance to vascular disease by expressing cell‐death‐inducing fungal elicitors in the xylem tissue

Plant Biotechnology Journal, EarlyView.
Summary Constitutive expression of hypersensitive cell‐death‐inducing effectors secreted by pathogens has proved to be difficult in plants. Herein, xylem‐specific promoters (PVND7 or PVND2) were utilized to express three cell‐death‐inducing proteins (FocSIX1A, FocSIX6 or TvSm1) of fungal origin in banana plants.
Sanjana Negi, Himanshu Tak, Subham Bhakta, Mahesh Tiwari, Thumballi Ramabhatta Ganapathi, Sudhir Singh, Anand Ballal   +6 more
wiley   +1 more source

Non‐coding RNAs in plant stress responses: molecular insights and agricultural applications

Plant Biotechnology Journal, EarlyView.
Summary Non‐coding RNAs (ncRNAs) have emerged as crucial regulators in plant responses to environmental stress, orchestrating complex networks that finetune gene expression under both abiotic and biotic challenges. To elucidate this intricate ncRNA crosstalk, this review comprehensively summarizes recent advances in understanding the mechanisms of key ...
Xiaotong Chen, Zhaohui Chen, Ryan Watts, Hong Luo   +3 more
wiley   +1 more source