Results 31 to 40 of about 39,010 (245)

C-type lectins in immunity and homeostasis

Nature Reviews Immunology, 2018
The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of physiological functions. Most research attention has focused on the ability of C-type lectins to function in innate and adaptive antimicrobial immune responses, but these proteins are increasingly being recognized to have a
Brown, Gordon D, Willment, Janet A, Whitehead, Lauren   +2 more
openaire   +4 more sources

Integrative analysis workflow for the structural and functional classification of C-type lectins

BMC Bioinformatics, 2011
Background It is important to understand the roles of C-type lectins in the immune system due to their ubiquity and diverse range of functions in animal cells.
Koh Geoffrey, Low Ariana, Poh Daren, Yao Yujian, Ng Say, Wong Victor, Vagenende Vincent, Lam Kong-Peng, Lee Dong-Yup   +8 more
doaj   +1 more source

Role of Lectin in the Response of Aedes aegypti Against Bt Toxin

Frontiers in Immunology, 2022
Aedes aegypti is one of the world’s most dangerous mosquitoes, and a vector of diseases such as dengue fever, chikungunya virus, yellow fever, and Zika virus disease.
Intikhab Alam, Intikhab Alam, Intikhab Alam, Khadija Batool, Khadija Batool, Aisha Lawan Idris, Aisha Lawan Idris, Weilong Tan, Xiong Guan, Xiong Guan, Lingling Zhang, Lingling Zhang   +11 more
doaj   +1 more source

The Roles of Direct Recognition by Animal Lectins in Antiviral Immunity and Viral Pathogenesis

Molecules, 2015
Lectins are a group of proteins with carbohydrate recognition activity. Lectins are categorized into many families based on their different cellular locations as well as their specificities for a variety of carbohydrate structures due to the features of ...
Yang Liu, Jianying Liu, Xiaojing Pang, Tao Liu, Zhijie Ning, Gong Cheng   +5 more
doaj   +1 more source

Transgenic Expression of Human C-Type Lectin Protein CLEC18A Reduces Dengue Virus Type 2 Infectivity in Aedes aegypti

Frontiers in Immunology, 2021
The C-type lectins, one family of lectins featuring carbohydrate binding domains which participate in a variety of bioprocesses in both humans and mosquitoes, including immune response, are known to target DENV.
Lie Cheng, Lie Cheng, Wei-Liang Liu, Yun-Ting Tsou, Jian-Chiuan Li, Chia-Hao Chien, Matthew P. Su, Kun-Lin Liu, Ya-Lang Huang, Shih-Cheng Wu, Jih-Jin Tsai, Jih-Jin Tsai, Jih-Jin Tsai, Shie-Liang Hsieh, Shie-Liang Hsieh, Shie-Liang Hsieh, Shie-Liang Hsieh, Chun-Hong Chen, Chun-Hong Chen   +18 more
doaj   +1 more source

High Bacterial Agglutination Activity in a Single-CRD C-Type Lectin from Spodoptera exigua (Lepidoptera: Noctuidae)

Biosensors, 2017
Lectins are carbohydrate-interacting proteins that play a pivotal role in multiple physiological and developmental aspects of all organisms. They can specifically interact with different bacterial and viral pathogens through carbohydrate-recognition ...
Leila Gasmi, Juan Ferré, Salvador Herrero   +2 more
doaj   +1 more source

Lectins bring benefits to bones

eLife, 2016
The discovery that proteins called c-type lectins promote bone growth could lead to new treatments for age-related bone disorders.
Charles KF Chan, Ryan C Ransom, Michael T Longaker   +2 more
doaj   +1 more source

Partial Characterization of Lectins Purified from the Surco and Vara (Furrow and Rod) Varieties of Black Phaseolus vulgaris

Molecules, 2022
As they manifest specifically and reversibly, lectins are proteins or glycoproteins with the characteristic of agglutinating erythrocytes. Given that grain legume lectins can represent 10% of protein content and can have various biological functions ...
Carmen Valadez-Vega, Olivia Lugo-Magaña, Gabriel Betanzos-Cabrera, José Roberto Villagómez-Ibarra   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source