Results 231 to 240 of about 38,146 (244)
Some of the next articles are maybe not open access.
2012
Historically the C-Type lectins (CLEC) or C-type lectin receptors (CLR) form a family of Ca2+ dependent carbohydrate binding proteins which have a common sequence motif of 115–130 amino acid residues, referred to as the carbohydrate recognition domain (CRD). The C-type designation is from their requirement for calcium for binding.
Anita Gupta, G. S. Gupta
openaire +1 more source
Historically the C-Type lectins (CLEC) or C-type lectin receptors (CLR) form a family of Ca2+ dependent carbohydrate binding proteins which have a common sequence motif of 115–130 amino acid residues, referred to as the carbohydrate recognition domain (CRD). The C-type designation is from their requirement for calcium for binding.
Anita Gupta, G. S. Gupta
openaire +1 more source
Role of C-Type Lectins in Mycobacterial Infections
Current Drug Targets, 2008Worldwide clinical cases due to multi drug- and extensively drug-resistant strains of Mycobacterium tuberculosis (M.tb) are increasing making the need for new therapies more critical than ever. A major obstacle for designing new drugs to treat mycobacterial infections is our limited knowledge of the interface between the bacillus (especially M.tb) and ...
J B, Torrelles +4 more
openaire +2 more sources
An evolutionary perspective on C‐type lectins in infection and immunity
Annals of the New York Academy of Sciences, 2012Host–pathogen interactions have coevolved for many years. On the one hand, the human immune system consists of innate and adaptive immune cells that function to defeat pathogens, and on the other hand, pathogens have coevolved to use the system for their own propagation.
van den Berg, Linda M. +2 more
openaire +2 more sources
A Family of C-Type Lectins in Manduca sexta
2001Insects have a rapid and effective immune system against microbial infections (Gillespie et al., 1997) that shares common characteristics with the innate immune system of vertebrates. It also consists of humoral and cellular responses. In the cellular responses such as phagocytosis, nodule formation and encapsulation, hemocytes play important roles. In
X Q, Yu, M R, Kanost
openaire +2 more sources
Classification of C‐Type Lectins and Recognition of Pathogens
Microbiology and ImmunologyABSTRACT C‐type lectins are calcium‐dependent glycan‐binding proteins that play key roles in the innate immune response by recognizing pathogens. Soluble C‐type lectins agglutinate and neutralize pathogens, activate the complement system, and promote pathogen clearance via opsonization.
openaire +2 more sources
Immunobiology of C-Type Lectin Receptors
2013C-type lectin receptors (CLRs) that signal via the kinase Syk are an important class of pattern recognition receptors in the innate immune system. They recognize pathogen- and host-derived danger signals, and are best known for their role in antifungal immunity.
Susanne Roth +2 more
openaire +1 more source