Results 201 to 210 of about 38,156 (244)

A Pancreatic Ductal Adenocarcinoma Diagnostic System Using Serum Extracellular Vesicle Detection with Optimized Lectin Combination Using Machine Learning. [PDF]

Cancers (Basel)
Kawakami T, Uemura S, Ono M, Horikoshi K, Kuno A, Kashiro A, Honda K, Nagashima K, Kumada K, Munekage M, Seo S, Furihata K, Furihata M, Honke K, Kitago M, Kitagawa Y, Suematsu M, Itonaga M, Kabe Y.   +18 more
europepmc   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Histochemical Properties of the Vomeronasal System in Hokkaido Sika Deer (<i>Cervus nippon yesoensis</i>). [PDF]

Animals (Basel)
Kondoh D, Arimura T, Arakaki M, Otake Y, Kanagawa T, Tomiyasu J.   +5 more
europepmc   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Concanavalin A targets phylogenetically conserved N-linked glycans on coronavirus spike proteins for broad-spectrum antiviral activity. [PDF]

J Virol
Guo D, Yu S, Ma K, Tao H, Wang Q, Han S, Ai Q, Hu H, Ma X, Li G, Wang S.   +10 more
europepmc   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

Preclinical Risk Assessment of Plant Lectins with Pharmacological Applications: A Narrative Review. [PDF]

Molecules
Marinho AO, da Silva MNB, da Silva SP, Nova ICV, Costa JAD, Paiva PMG, de Albuquerque LP, Pontual EV, Patriota LLS, Napoleão TH.   +9 more
europepmc   +1 more source

Neuraminidase of influenza A viruses induces global desialylation of host cells via its intracellular function. [PDF]

Microbiol Spectr
Kobayashi D, Hiono T, Isoda N, Sakoda Y.
europepmc   +1 more source