Results 171 to 180 of about 67,545 (209)

C-Type Lectin Receptors in Antifungal Immunity

2020
Most fungal species are harmless to humans and some exist as commensals on mucocutaneous surfaces. Yet many fungi are opportunistic pathogens, causing life-threatening invasive infections when the immune system becomes compromised. The fungal cell wall contains conserved pathogen-associated molecular patterns (PAMPs), which allow the immune system to ...
Christina, Nikolakopoulou, Janet A, Willment, Gordon D, Brown   +2 more
openaire   +2 more sources

C-Type Lectin Receptors Orchestrate Antifungal Immunity

Future Microbiology, 2013
Fungal infections are an emerging threat for human health. A coordinated host immune response is fundamental for successful elimination of an invading fungal microbe. A panel of C-type lectin receptors expressed on antigen-presenting dendritic cells enable innate recognition of fungal cell wall carbohydrates and tailors adaptive responses via the ...
Brigitte A, Wevers, Teunis B H, Geijtenbeek, Sonja I, Gringhuis   +2 more
openaire   +2 more sources

Insect C-type lectins in innate immunity

Developmental & Comparative Immunology, 2018
C-type lectins (CTLs) are a family of proteins that contain characteristic modules of carbohydrate-recognition domains (CRDs) and they possess the binding activity to ligands in a calcium-dependent manner. CTLs play important roles in animal immune responses, and in insects, they are involved in opsonization, nodule formation, agglutination ...
Xiaofeng Xia, Minsheng You, Xiang-Jun Rao, Xiao-Qiang Yu   +3 more
openaire   +2 more sources

Myeloid C-type lectins in innate immunity

Nature Immunology, 2006
C-type lectins expressed on myeloid cells comprise a family of proteins that share a common structural motif, and some act as receptors in pathogen recognition. But just as the presence of leucine-rich repeats alone is not sufficient to define a Toll-like receptor, the characterization of C-type lectin receptors in innate immunity requires the ...
Robinson, Matthew J, Sancho, David, Slack, Emma C, LeibundGut-Landmann, Salomé, Sousa, Caetano Reis e   +4 more
openaire   +2 more sources

C-Type Lectin (C-Type Lectin Receptor)

2022
openaire   +1 more source

Type 2 chronic inflammatory diseases: targets, therapies and unmet needs

Nature Reviews Drug Discovery, 2023
P V Kolkhir, Thomas Bieber, Giorgio Walter Canonica   +2 more
exaly  

Reptile C-Type Lectins

2009
Xiao-Yan Du, Kenneth Clemetson
openaire   +1 more source

Targeting inflammation in the treatment of type 2 diabetes: time to start

Nature Reviews Drug Discovery, 2014
Marc Y Donath
exaly  

Immunomodulatory therapy to preserve pancreatic β-cell function in type 1 diabetes

Nature Reviews Drug Discovery, 2011
Frank D Waldron-Lynch
exaly  

C-type Lectins

2011
openaire   +1 more source