Results 101 to 110 of about 24,283,061 (186)

Secondary Sites of the C‐type Lectin‐Like Fold

Chemistry – A European Journal
AbstractC‐type lectins are a large superfamily of proteins involved in a multitude of biological processes. In particular, their involvement in immunity and homeostasis has rendered them attractive targets for diverse therapeutic interventions. They share a characteristic C‐type lectin‐like domain whose adaptability enables them to bind a broad ...
Lefèbre, Jonathan, Falk, Torben, Ning, Yunzhan, Rademacher, Christoph   +3 more
openaire   +5 more sources

Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins [PDF]

, 2004
The mouse (m) DC-SIGN family consists of several homologous type II transmembrane proteins located in close proximity on chromosome 8 and having a single carboxyl terminal carbohydrate recognition domain.
Yashima, Yusuke, Omatsu, Yoshiki, Takahara, Kazuhiko   +2 more
core  

C-type lectins from the venom of the Southern Pacific rattlesnake as therapeutic agents for blood clotting disorders

, 2018
Several protein groups including C-type lectin-like proteins constitute many snake venoms. Snake venom C-type lectins have been shown to inhibit platelet function, coagulation factors, cell adhesion, cell migration and cell invasion.
Walls, Robert I.
core  

Use of Natural and Synthetic Glycolipid Libraries in Defining Lectins from Pathogens

, 2007
Lectins: Analytical Technologies covers both analytical and biological aspects of lectins (functional carbohydrate (complex sugar) recognition proteins) and provides researchers in the field with a resource containing background information and 'look-up'
Natunen, Jari, Niemelä, Ritva, Helin, Jari, Weikkolainen, Krista, Miller-Podraza, Halina,   +4 more
core  

Biophysical Studies of Pathogen Recognition by C-Type Lectins

, 2009
C-type lectins are a prominent class of pathogen recognition receptors in the innate immune system. The three pathogen recognition lectins studied in this thesis are the mannose binding protein (MBP), the dendritic cell-specific ICAM-3 grabbing ...
Menon, Sindhu
core  

C-type lectins in HIV-1 infection

Retrovirology, 2011
Geijtenbeek Teunis BH
doaj   +1 more source

ASGR2 AND CLEC12A C TYPE LECTINS: NEW PLAYERS IN GLIOBLASTOMA IMMUNOSUPPRESSIVE NETWORKS

BACKGROUND-AIM Glioblastoma (GBM) is the most fathal brain tumor in adults with poor survival and no effective treatment. Dissecting immunosuppressive mechanisms in GBM is crucial to identify novel therapeutic targets.
A. Santoro, I. G. Zizzari, A. Pace, A. Rughetti, C. Napoletano, M. Nuti, L. D'Angelo, L. Farina, M. Petti, C. Alfano   +9 more
core  

A N-Acetyl-D-Glucosamine-Binding C-Type Lectin in the Cutaneous Mucus of Chub Mackerel, Scomber japonicus, Agglutinates Pathogenic Bacteria. [PDF]

Microbiol Immunol
Tsutsui S, Kunisaki T, Izawa T, Nakamura O.   +3 more
europepmc   +1 more source

A glycosaminoglycan microarray identifies galectin-4 binding to sulfated glycosaminoglycans. [PDF]

Biochem Biophys Rep
Sano K, Nagatomo M, Shigematsu K, Yamasaki K, Anh DXT, Shibuya A, Otsuka Y, Minamisawa T, Tateno H.   +8 more
europepmc   +1 more source

Synthesis of a multivalent α-1,2-mannobiose ligand for targeting C-type lectins

The importance of lectins in biological processes such as pathogen recognition, cell adhesion, and cell recognition is well documented. C-Type lectins, which require calcium for binding, play an important role in the innate immune response by engaging ...
Snyder, Nicole L., Hartmann, Laura, Langer, Jannis   +2 more
core   +1 more source