Results 231 to 240 of about 1,772,176 (315)

Plant defense strategies: The dual armor of disease resistance and tolerance

New Plant Protection, EarlyView.
Plants employ dual strategies against pathogens: Resistance limits invasion via immune responses, whereas tolerance mitigates damage to sustain growth—together enhancing survival under infections. Abstract Pathogen infections pose a significant threat to plant health, global food security, and ecosystems.
Zhijuan Tang, Shaosong Shi, Xinyu Du, Guoyong Xu   +3 more
wiley   +1 more source

A trifunctional probe for generation of fluorogenic glycan-photocrosslinker conjugates. [PDF]

RSC Chem Biol
Vreulz B, De Crozals D, Cecioni S.
europepmc   +1 more source

Isolation, Characterization, and Wound‐Healing Potential of β‐D‐Glucan from Lycoperdon pyriforme Schaeff

ChemistryOpen, EarlyView.
Mushrooms have become a prominent focus in alternative medicine and are now the subject of increasingly detailed scientific investigation. This study explores the isolation, purification, and characterization of β‐D‐glucan from Lycoperdon pyriforme, with particular emphasis on its wound‐healing potential. The aim of this research is to isolate, purify,
Elif Yavuz‐Dokgöz, Meltem Güleç, Burçin İzbudak, Onur Şahin, Ayça Bal‐Öztürk   +4 more
wiley   +1 more source

Mitochondrial Glycosylation in Neuroinflammation Models. [PDF]

Cells Tissues Organs
Madabhushi M, Murphy RE, Ali MA, Paneerselvam M, Patil MH, Tyrrell DJ, Samal J.   +6 more
europepmc   +1 more source

TREM2 Downregulation Disrupts Microglial Function and Synaptic Pruning Through RA/RARα Signaling: Mechanisms Underlying Autism‐Like Behaviors

Pediatric Discovery, EarlyView.
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu, Kexin Bai, Yali Bai, Yuan Miao, Tingjiao Zhao, Yi Yang, Jie Chen, Ting Yang, Tingyu Li, Hua Wei   +9 more
wiley   +1 more source

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

PROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre, Jens Hamar, Monica B. Urias, Dietmar Kültz   +3 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Photopharmacology beyond azobenzene photoswitches

Responsive Materials, EarlyView.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo, Jinghong Dai, Long Deng, Zhiwei Zhang, He Tian, Junji Zhang   +5 more
wiley   +1 more source

Combination of 3D Micro Contact Printing and Scraping Technique for Site Selective Cocultivation Across a Porous Micro Structured Scaffold

Small, EarlyView.
The study by Brauer et al. presents an operationally simple scraping technique in combination with 3D‐µCP to generate 3D cell patterns on both, front and the reverse side of a micro thermoformed substrate. It can be used to study cell‐to‐cell crosstalk at the microlevel with topographies similar to real tissue. Abstract 3D‐microcontact printing (3D‐µCP)
Dana Brauer, Anni Peng, Justyna Borowiec, Jörg Hampl, Shannon Prehl, Maren Klett, Merle Johanna Küstner, Frank Weise, Andreas Schober, Sukhdeep Singh   +9 more
wiley   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source