Results 261 to 270 of about 1,772,176 (315)

Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis

Andrology, EarlyView.
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz, Takahiro Yamanaka, Shahrina Akter, Masanori Koyago, Masayuki Shimada   +4 more
wiley   +1 more source

Phenotypic and safety exploration of indigenous bacterial strains for probiotic applications in aquaculture. [PDF]

BMC Microbiol
Rwezawula P, Mwanja WW, Raj JRM, Karunasagar I, Bossier P, Vanrompay D.   +5 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Legume lectin phytohemagglutinin reduces transepithelial electrical resistance by counteracting the chaperone function of heat shock protein-70. [PDF]

J Nutr Sci
Dokladny K, Setty P, Moseley PL, Lin HC.
europepmc   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

Brain Pathology, EarlyView.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau, Rebecca Crisp, Mallory Keating, Elizabeth Ochoa, Timothy E. Richardson, Margaret E. Flanagan, Jamie M. Walker, Sarah C. Hopp, Kevin F. Bieniek   +8 more
wiley   +1 more source

Utilization of Fish Byproduct in Edible Films: A Sustainable Approach to Improving Fillet Shelf Life. [PDF]

Food Sci Nutr
Alak G, Kara A, Altıntaş R, Şişecioğlu M.   +3 more
europepmc   +1 more source

Comprehensive Colorectal Cancer Stem Cell Transcriptomic Signatures That Can Predict Patient Prognostic Outcomes

Cancer Science, EarlyView.
We characterized colorectal cancer stem‐like cell (CRC‐SC)–derived transcriptomic subtypes based on mRNA expression of 57 patient‐derived SC lines. Expression profiles were compared with normal colonic epithelium stem‐like cells (NCE‐SCs), yielding differentially expressed genes.
Fumihiko Kakizaki, Hiroyuki Miyoshi, Takehito Yamamoto, Tomonori Morimoto, Hiroyuki Matsubara, Shoichi Kitano, Tadayoshi Yamaura, Hisatsugu Maekawa, J. B. Brown, Tosiya Shun Sato, Kazutaka Obama, Yoshiharu Sakai, Kenji Kawada, Makoto Mark Taketo   +13 more
wiley   +1 more source

Replacing protruding domains of MrNV virus-like particles with sialic acid binding domains enhances binding to SARS-CoV-2 susceptible cells and reduces pseudovirus infection. [PDF]

Sci Rep
Boonkua S, Thongsum O, Chantunmapitak R, Soongnart P, Jaranathummakul S, Srisanga K, Wongtrakoongate P, Asuvapongpatana S, Weerachatyanukul W, Watthammawut A, Somrit M.   +10 more
europepmc   +1 more source

Identification of BCL2L11 as a Candidate Gene for Hereditary Predisposition to Non‐Medullary Thyroid Cancer Using Familial Whole‐Exome‐Sequencing

Clinical Genetics, EarlyView.
Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Duygu Abbasoglu, Mathis Lepage, Nicolas Sonnier, Sandrine Viala, Nancy Uhrhammer, Flora Ponelle‐Chachuat, Anne Cayre, Maud Privat, Mathias Cavaillé, Yannick Bidet   +9 more
wiley   +1 more source

Tumor glyco-immunology, glyco-immune checkpoints and immunotherapy. [PDF]

J Immunother Cancer
Pinho SS, Macauley MS, Läubli H.
europepmc   +1 more source