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Role of C-Type Lectins in Mycobacterial Infections
Current Drug Targets, 2008Worldwide clinical cases due to multi drug- and extensively drug-resistant strains of Mycobacterium tuberculosis (M.tb) are increasing making the need for new therapies more critical than ever. A major obstacle for designing new drugs to treat mycobacterial infections is our limited knowledge of the interface between the bacillus (especially M.tb) and ...
J B, Torrelles +4 more
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A Family of C-Type Lectins in Manduca sexta
2001Insects have a rapid and effective immune system against microbial infections (Gillespie et al., 1997) that shares common characteristics with the innate immune system of vertebrates. It also consists of humoral and cellular responses. In the cellular responses such as phagocytosis, nodule formation and encapsulation, hemocytes play important roles. In
X Q, Yu, M R, Kanost
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Classification of C‐Type Lectins and Recognition of Pathogens
Microbiology and ImmunologyABSTRACT C‐type lectins are calcium‐dependent glycan‐binding proteins that play key roles in the innate immune response by recognizing pathogens. Soluble C‐type lectins agglutinate and neutralize pathogens, activate the complement system, and promote pathogen clearance via opsonization.
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