Results 11 to 20 of about 38,146 (244)

C-type lectins and phagocytosis

open access: yesImmunobiology, 2009
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
openaire   +3 more sources

Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. [PDF]

open access: yesPLoS Pathogens, 2014
C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.
Yang Liu   +8 more
doaj   +1 more source

The immune role of C-type lectins in molluscs [PDF]

open access: yesInvertebrate Survival Journal, 2011
The phylum Mollusca is one of the largest and most important group in the animal kingdom. Recently, interest in molluscan immunity has increased due to their importance in worldwide aquaculture, their role in aquatic environmental science and their ...
L Wang, L Wang, M Huang, H Zhang, L Song
doaj   +1 more source

Lectins with Anti-HIV Activity: A Review

open access: yesMolecules, 2015
Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity.
Ouafae Akkouh   +7 more
doaj   +1 more source

Functional characterisation and comparative analysis of two C-type lectins with different key motifs from mud crab

open access: yesAquaculture Reports, 2022
C-type lectins are pattern recognition receptors (PRRs) involved in innate immunity. They possess one or more carbohydrate recognition domains (CRDs) belonging to Ca2+-dependent carbohydrate binding proteins.
Jingwen Liu   +8 more
doaj   +1 more source

Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin

open access: yesToxins, 2011
The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure.
Emily Gage   +4 more
doaj   +1 more source

Immune characterization and expression analysis of a C-type lectin from Pinctada fucata martensii

open access: yesAquaculture Reports, 2023
C-type lectins are involved in nonself-recognition and pathogen clearance, and play an important role in innate immunity. Pinctada fucata martensii, which is an important shellfish in the pearl industry, is being attacked by pathogenic microorganisms ...
Zhijie Guo   +5 more
doaj   +1 more source

Lectins with Potential for Anti-Cancer Therapy

open access: yesMolecules, 2015
This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau   +3 more
doaj   +1 more source

C-type lectins in immunity and homeostasis

open access: yesNature Reviews Immunology, 2018
The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of physiological functions. Most research attention has focused on the ability of C-type lectins to function in innate and adaptive antimicrobial immune responses, but these proteins are increasingly being recognized to have a
Brown, Gordon D   +2 more
openaire   +4 more sources

C-Type Lectins Link Immunological and Reproductive Processes in Aedes aegypti

open access: yesiScience, 2020
Summary: Physiological trade-offs between mosquito immune response and reproductive capability can arise due to insufficient resource availability. C-type lectin family members may be involved in these processes.
Hsing-Han Li   +9 more
doaj   +1 more source

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