Results 211 to 220 of about 148,943 (340)

Exopolysaccharides From Lactobacillus delbrueckii subsp. bulgaricus OLL1073R‐1 Enhance Macrophage Bactericidal Activity Through IL‐12‐Dependent Macrophage–NK Cell Crosstalk

Microbiology and Immunology, EarlyView.
ABSTRACT Exopolysaccharides (EPS) produced by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R‐1 have been reported to exert immunomodulatory effects, primarily in antiviral responses; however, their role in antibacterial host defense remains unclear. Here, we investigated whether EPS enhance macrophage‐mediated killing of Streptococcus pyogenes, a
Chikara Kohda, Hiroki Ishikawa, Yoshihiro Kuno, Yasunari Matsuzaka, Hiroki Kono, Toshihiro Sashihara, Hirotaka Kuwata, Masayuki Iyoda   +7 more
wiley   +1 more source

LeGenD: High-throughput N-glycan profiling using explainable AI and lectin profiling. [PDF]

J Biol Chem
Li H, Peralta AG, Schoffelen S, Hansen AH, Arnsdorf J, Schinn SM, Skidmore J, Choudhury B, Rocamora F, Paulchakrabarti M, Voldborg BG, Chiang AWT, Lewis NE.   +12 more
europepmc   +1 more source

Chromosome‐Level Genome Assembly of Strauchbufo raddei and Multi‐Omic Insights Into Drought Adaptation

Integrative Zoology, EarlyView.
ABSTRACT Understanding how amphibians adapt to terrestrial and arid environments is important for elucidating vertebrate terrestrialization. In this study, we present the first chromosome‐level, high‐quality genome assembly of Strauchbufo raddei, constructed using PacBio HiFi long‐read sequencing and Hi‐C scaffolding. The assembled genome is 4.47 Gb in
Fanrui Chen, Rui Su, Chengqi Wang, Shengnan Wang, Jinjing Wang, Yuquan Miao, Wenya Zhang, Wei Zhao   +7 more
wiley   +1 more source

Development and validation of a lectin-based assay for detection of IgG Fc glycosylation as a biomarker in lupus nephritis. [PDF]

Lupus Sci Med
Upadhyay R, Gao J, Orellana Enamorado AMM, Wenderfer SE, Tsokos GC, Bhargava R.   +5 more
europepmc   +1 more source

Plant lectins, from ancient sugar‐binding proteins to emerging anti‐cancer drugs in apoptosis and autophagy

Cell Proliferation, 2015
Q. Jiang, S. Zhang, M. Tian, S.-Y. Zhang, T. Xie, D.-Y. Chen, Y.-J. Chen, J. He, J. Liu, L. Ouyang, X. Jiang   +10 more
semanticscholar   +1 more source

HGTScanner: Detecting horizontal gene transfer at the fine scale using whole organelle genomes

Methods in Ecology and Evolution, EarlyView.
Abstract Horizontal gene transfer (HGT) has profoundly shaped eukaryotic organellar genomes like plant mitochondria. Yet no generalized tools are currently available to efficiently characterize HGT across these genomes due to both high structural complexity and low sequence divergence compared to prokaryotic HGTs.
Liming Cai, Rachel O. Cohen
wiley   +1 more source

Applications of Plant Lectins in Detection and Targeted Therapy of Urological Cancers. [PDF]

Drug Des Devel Ther
Long Z, Li Q, Shi F, Li F, Zang J.
europepmc   +1 more source

Lupus Panniculitis Immunoprofiling Reveals a Cytotoxic, Type 1‐Skewed T‐Cell Response With Signs of Metabolic Alteration

Allergy, EarlyView.
Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri, Reihane Ziadlou, Stephan Traidl, Milena Sokolowska, Emmanuel Contassot, Nick Li, Maija Kiuru, Isabel Kolm, Werner Kempf, Emanual Maverakis, Cezmi Akdis, Marie‐Charlotte Brüggen   +11 more
wiley   +1 more source

Exploring glycocalyx components powering the contact between Entamoeba histolytica and bacteria during non-opsonic phagocytosis. [PDF]

PLoS Pathog
Labruyère E, Treport T, Olivo-Marin JC, Guillen N.   +3 more
europepmc   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source