FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
Structural Characterization of a Proto-Type Galectin from <i>Cinachyrella</i> sp. and Evaluation of Its Selective Bacterial Glycan Recognition and Antibiofilm Activity. [PDF]
Marques JSN +13 more
europepmc +1 more source
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson +4 more
wiley +1 more source
IgG N-glycosylation in autoimmune diseases. [PDF]
Pumpe C, Vermeren S.
europepmc +1 more source
Breaking the ice: multiple origins of ice‐binding/antifreeze proteins
Ice‐binding proteins (IBPs) evolved independently in many organisms during Cenozoic cooling and glaciation. In flounders, α‐helical IBPs evolved from an antiviral protein, while similar IBPs arose independently from different progenitors in three other fish lineages.
Laurie A. Graham, Peter L. Davies
wiley +1 more source
Comparative proteomic analysis of the zebrafish (Danio rerio) perivitelline fluid; identifying putative cortical alveoli-associated proteins. [PDF]
Lewis BA +4 more
europepmc +1 more source
ABSTRACT Background and Aims Patients with chronic hepatitis C and advanced fibrosis remain at substantial risk of hepatocellular carcinoma (HCC) and non‐liver–related death even after sustained virological response (SVR) to direct‐acting antivirals (DAA).
Daisuke Sakon +19 more
wiley +1 more source
Molecular Cloning and Functional Analysis of CTL14 and PPO4: Their Roles in Development, Reproduction, and Antiviral Defense in <i>Hyphantria cunea</i>. [PDF]
Faidah AN, Lu T, Wang Q, Sun L, Cao C.
europepmc +1 more source
Identification of Glycosylation-Associated Proteins in Colostrum: A Review of Mass Spectrometry-Based Strategies. [PDF]
Drewek I, Chazarin B, Wattiez R.
europepmc +1 more source
Chemical Characterization and In Vivo Safety Assessment of Aqueous Extract From Anacardium occidentale L. (Anacardiaceae) Leaves. [PDF]
Bento EFL +11 more
europepmc +1 more source

