Results 261 to 270 of about 120,943 (337)

Cascade Ultrasonic Cavitation Enables Microbubble–Nanoparticle Hybrid to Broadly Accumulate and Penetrate into Pancreatic Ductal Adenocarcinoma

Small Structures, EarlyView.
A novel cascade twice ultrasonic cavitation strategy utilizing macrophage membrane‐modified microbubble‐nanoparticle hybrid (MMB@TFHPD) is engineered to enhance drug delivery efficiency in pancreatic ductal adenocarcinoma. The system implements sequential ultrasound applications: initially disrupting the blood–tumor barrier, followed by triggering deep
Dequan Ye, Guowei Wang, Xiao Liu, Yijie Chen, Jifan Chen, Hua Yin, Yuhan Fu, Fei Gao, Lina Tang, Pintong Huang   +9 more
wiley   +1 more source

In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging. [PDF]

Nat Commun
Liu X, Ma J, Zhang Y, Xu Y, Wang Y, Yang D, Wang D, Liu Q, Zhang F.   +8 more
europepmc   +1 more source

Emerging trends in the management of non‐obstructive azoospermia

UroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad, Mohamed Alkabeer, Dina Abdelmonim, Sameh Fayek GamalElDin, Mohamed Wael Ragab   +4 more
wiley   +1 more source

The Promising Role of Plant-Derived Lectins in Oral Cancer Therapeutics: A Systematic Review. [PDF]

Cureus
Ramsridhar S, Rajkumar C, Balasubramaniam M, Anandan S, Sabesan M, Jayamani L.   +5 more
europepmc   +1 more source

Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediated glycan modulation

VIEW, Volume 6, Issue 3, June 2025.
Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan, Zhedong Yang, Li Cao, Jinyuan Zhang, Fei Wu, Miaomiao Xin, Bo Guo, Lumin Wang, Lingyu Zhao, Yannan Qin, Chengcheng Liu   +10 more
wiley   +1 more source

Transmitted/founder (T/F) HIV-1 derived from sexual contact exhibits greater transmission fitness in human cervical tissue than T/F HIV-1 from blood-to-blood contact: Unique glycan profiles on T/F envelopes associated with transmission phenotypes. [PDF]

PLoS Pathog
Zhang Y, Klein K, Ratcliff A, Galappaththi SL, Hathaway N, Twells N, Patel M, Temesy S, Bailey JA, Mahal LK, Creuzenet C, Arts EJ.   +11 more
europepmc   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

VIEW, Volume 6, Issue 3, June 2025.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

Visualizing the endothelial glycocalyx in human glioma vasculature. [PDF]

Brain Tumor Pathol
Ohmura K, Tomita H, Okada H, Nakayama N, Ohe N, Izumo T, Hara A.   +6 more
europepmc   +1 more source

Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection

Insect Science, EarlyView.
Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido, Mónica Aquilino, David Buckley, José L. Bella, Rosario Planelló   +4 more
wiley   +1 more source

Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19

Aging Cell, EarlyView.
(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura, Lícia Torres, Giovanna Caliman Camatta, Jofer Zamame, Monique Macedo Coelho, Cecília Horta Ramalho‐Pinto, João Gervazio, Felipe Caixeta, Leandro Nascimento, Mariana Almeida Oliveira, Vinícius Dantas Martins, Marcos Felipe Oliveira, Murilo Soares Costa, Hugo Itaru Sato, Henrique Cerqueira Guimarães, Rafael Calvão Barbuto, Ana Paula Rocha Veiga, Najara Ataíde, Gabriela Prandi Caetano, Sarah Rangon, Mauro Lúcio O. Júnior, Fernanda Calvo Fortes, Luciana Zuccherato, Elaine Speziali, Olindo Assis Martins‐Filho, Verônica Coelho, Roberto Avritchir, Rafael Souza, Marina Ayupe, Caio Loureiro, Maria Eduarda Passos, Ana Clara Mota Neves, Pauline Leite, Santuza Maria Ribeiro Teixeira, Unaí Tupinambás, Liza Figueiredo Felicori, Gabriela Silveira‐Nunes, Tatiani Uceli Maioli, Denise Morais Fonseca, Andrea Teixeira‐Carvalho, Ana Maria Caetano Faria   +40 more
wiley   +1 more source