Results 41 to 50 of about 64,311 (254)

Towards defining the role of glycans as hardware in information storage and transfer: Basic principles, experimental approaches and recent progress [PDF]

, 2001
The term `code' in biological information transfer appears to be tightly and hitherto exclusively connected with the genetic code based on nucleotides and translated into functional activities via proteins.
Jiménez-Barbero, J., Romero, A., Gabius, Hans-Joachim, Siebert, H.-C., Solís, Dolores, Kaltner, H., Lieth, Claus-Wilhelm von der   +6 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Are Vicilins Another Major Class of Legume Lectins?

Molecules, 2014
Legume lectins comprise a structurally related, Ca/Mn-dependent, widespread, abundant and well characterized lectin family when compared to the large number of lectins from other sources described in the literature. Strangely enough, no specific function
Ana C. Ribeiro, Sara V. Monteiro, Belmira M. Carrapiço, Ricardo B. Ferreira   +3 more
doaj   +1 more source

Differential cellular localization of lectins in the testes of dromedary camel (Camelus dromedarius) during active and inactive breeding seasons

BMC Veterinary Research, 2023
The reproductive activity of the male dromedary camel (Camelus dromedarius) as a seasonal breeder is affected by various seasonal changes that reflect on the reproductive performance. In the current study, we explored a differential cellular localization
Mahmoud S. Gewaily, Mohamed Gaber Abdallah, Norhan E. Khalifa, Ola A. Habotta, Ahmed E. Noreldin   +4 more
doaj   +1 more source

Production of Lectins from Marine Algae: Current Status, Challenges, and Opportunities for Non-Destructive Extraction

Marine Drugs, 2022
Marine algae are an excellent source of novel lectins. The isolation of lectins from marine algae expands the diversity in structure and carbohydrate specificities of lectins isolated from other sources.
Intan Mariana Maliki, Mailin Misson, Peik Lin Teoh, Kenneth Francis Rodrigues, Wilson Thau Lym Yong   +4 more
doaj   +1 more source

Binding and toxicity of plant lectins to insects [PDF]

, 2002
The toxicity of plant lectins to insects after oral ingestion was investigated by incorporating the proteins into insect diets. Bioassays carried out using an artificial diet system demonstrated that kidney bean (Phaseolus vulgaris) lectin (PHA) caused a
Woodhouse, Stephen David
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3

Frontiers in Molecular Biosciences, 2021
Glycolipids are present on the surfaces of all living cells and thereby represent targets for many protein receptors, such as lectins. Understanding the interactions between lectins and glycolipids is essential for investigating the functions of lectins ...
Lina Siukstaite, Lina Siukstaite, Anne Imberty, Winfried Römer, Winfried Römer, Winfried Römer   +5 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source