Results 51 to 60 of about 120,943 (337)

Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]

, 2011
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A Babino, AA Jeyaprakash, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, E Zenteno, EJM Damme Van, GF Springer, GF Springer, GF Springer, GWG Bird, K Puri, KA Kulkarni, KA Kulkarni, M Duk, M Duk, M Sarkar, N Taniguchi, N Vega, R Lotan, R Ravishankar, R Sankaranarayanan, R Zenteno, S Hirohashi, S Tollefsen, SH Itzkowitz, SI Hakomori, SI Hakomori, SI Hakomori, SJ Rinderle, T Singh, T Singh, T Singh, TR Transue, V Piller, W Wang, X Lee, Y Yoda   +42 more
core   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Production of Lectins from Marine Algae: Current Status, Challenges, and Opportunities for Non-Destructive Extraction

Marine Drugs, 2022
Marine algae are an excellent source of novel lectins. The isolation of lectins from marine algae expands the diversity in structure and carbohydrate specificities of lectins isolated from other sources.
Intan Mariana Maliki, Mailin Misson, Peik Lin Teoh, Kenneth Francis Rodrigues, Wilson Thau Lym Yong   +4 more
doaj   +1 more source

Lectin ligands: New insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins [PDF]

, 1998
The mysteries of the functions of complex glycoconjugates have enthralled scientists over decades. Theoretical considerations have ascribed an enormous capacity to store information to oligosaccharides, In the interplay with lectins sugar-code words of ...
Bovin, N. V., Burchert, M., Frank, M., Gabius, Hans-Joachim, Gilleron, M., Kaltner, Herbert, Kayser, G., Kozár, T., Lieth, Claus-Wilhelm von der, Siebert, H. C., Tajkhorshid, Emad, Vliegenthart, JFG   +11 more
core   +3 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Plant lectins, chemical and biological aspects

Memorias do Instituto Oswaldo Cruz, 1991
Lectins, carbohydrate-binding proteins of non-immune origin, that agglutinate cells or precipitate polysaccharides and glycoconjugates, are well distributed in nature, mainly in the Plant Kingdom.
Renato de Azevedo Moreira, Iracema Lima Ainouz, José Tadeu Abreu de Oliveira, Benildo Sousa Cavada   +3 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Production of lectin-affinity matrices for process-scale glycoprotein purification [PDF]

, 2011
A selection of prokaryotic lectins with a variety of glycan specificities and affinities have been identified, cloned, expressed in Eschericia coli and characterised.
Clarke, Paul A., Keogh, Damien, O'Connell, Michael, O'Connor, Brendan, Thompson, Roisin   +4 more
core  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Akos Horvath, Andre S, Andre S, Andre S, Andre S, Andre S, Arnusch CJ, Buttery R, Elad-Sfadia G, Gabius HJ, Gabius HJ, Gabius HJ, Hans-Joachim Gabius, Imre Trojan, Jan-Dirk Baumhäkel, Jozsef Furak, Kaltner H, Kayser K, Kayser K, Kayser K, Kayser K, Klaus Kayser, Kopitz J, Kornelia Szluha, Lahm H, Laszlo Tiszlavicz, Liu FT, Moon BK, Nangia-Makker P, Puglisi F, Rappl G, Rorive S, Sabine Andre, Sheikholeslam-Zadeh R, Siebert HC, Tamas Szöke   +35 more
core   +1 more source