Results 101 to 110 of about 4,950,651 (314)

Lysias, Isocrates and the Trierarchs of Aegospotami

open access: yes, 2019
Isocr. 18 could have hired Isocrates, and the speaker of Lys. 21 and Eryximachus could have hired Lysias as speechwriters for their rhetorical skills. However, it is probable that Isocrates’ choice to criticize the former colleagues of Isocr.
Kapellos, Angelos
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

UV-VIS tartományban működő LED-ek fényerejének vezeték nélküli szabályzásának tervezése és kivitelezése

open access: yes, 2020
Android alkalmazással Bluetooth kapcsolaton keresztül vezérelt mikrokontroller, ami LED-ek fényerejét szabályozza.N.I.villamosmérnökBSc ...
Tóth, Tibor
core  

Interconnessioni geografiche. Il dossier di candidatura di Matera, Capitale Europea della Cultura 2019

open access: yes, 2019
This paper intends to propose a brief reflection centred on the territory of Matera, winner of the qualification of European Capital of Culture for 2019.
Piras, Rachele
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Video corporatiu Led Dream

open access: yes, 2015
El projecte consisteix en realitzar un vídeo corporatiu sobre l’empresa LED Dream, dedicada a la venta de pantalles LED. El vídeo està format per una animació realitzada amb motion graphics amb la que s’explica el què fa l’empresa, els seus productes i ...
Martínez Rubiralta, Núria
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Led-alapú szabályozható, homogén megvilágítást adó fényforrás tervezése fizikai kísérletekhez

open access: yes, 2017
Homogén megvilágítás létrehozásának elméleti áttekintése. LED-ek alkalmazásának áttekintése (látható fény és UV tartományban) Homogén megvilágítás előállításához szükséges kísérletek elvégzése. A kísérletek alapján, a megvilágító rendszer megtervezése és
Czinke, Sándor
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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