Results 81 to 90 of about 1,703,563 (293)

The multi-modality cardiac imaging approach to the Athlete's heart: an expert consensus of the European Association of Cardiovascular Imaging [PDF]

, 2015
The term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive training in the
Abergel, Abhayaratna, Andersson, Angell, Bartram, Basavarajaiah, Blair, Bossone, Bruder, Caso, Chandra, Corrado, Corrado, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, Di Paolo, Douglas, Estorch, Fagard, Fagard, Florescu, Gabrielli, Galderisi, Galderisi, Garber, George, Gilbert, Goldhammer, Grothues, Hauser, Hildick-Smith, Kalliokoski, Kim, Knutsen, La Gerche, La Gerche, Ljungqvist, Mahrholdt, Makan, Maron, Maron, Maron, Maron, Maron, Matsumura, Matsuo, Montgomery, Moon, Moon, Morganroth, Mousavi, Nagueh, Nottin, O'Hanlon, Pattynama, Payne, Pelliccia, Pelliccia, Petersen, Pluim, Prakken, Rehr, Richand, Rickers, Rudski, Saghir, Scharf, Scharhag, Schwartz, Semelka, Sen-Chowdhry, Sen-Chowdhry, Severino, Sharma, Shave, Shave, Spirito, Steinvil, Teramoto, Terry, Thomas, Urhausen, Vinereanu, Whyte, Wolfe, Zeppilli, Zoncu   +91 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Current clinical applications of spectral tissue Doppler echocardiography (E/E' ratio) as a noninvasive surrogate for left ventricular diastolic pressures in the diagnosis of heart failure with preserved left ventricular systolic function [PDF]

, 2007
Congestive heart failure with preserved left ventricular systolic function has emerged as a growing epidemic medical syndrome in developed countries, which is characterized by high morbidity and mortality rates.
Stephane Arques, Emmanuel Roux, Roger Luccioni, TE Owan, M Galderisi, P Banerjee, J Remes, CS Wang, L Caruana, JM Cahill, SA Hunt, K Swedberg, MS Nieminen, MS Maurer, JK Oh, F Bursi, RD Okada, DW Kitzman, JT Reeves, CP Cheng, CP Cheng, P Faggiano, AC Guyton, KA Gaar Jr, OR Levine, GM Verghese, Y Berthiaume, EC Rackow, S Arques, S Arques, S Nanas, PD Sutcliffe, C Tschope, DB Chomsky, S Puri, P Agostoni, E Agricola, M Guazzi, E Picano, MD Kraemer, JS Gottdiener, RL Bess, Y Ishida, CY Choong, JD Thomas, DW Sohn, SR Ommen, SF Nagueh, S Arques, L Sundereswaran, SF Nagueh, SF Nagueh, DW Sohn, YJ Kim, F Gonzalez-Vilchez, C Rivas-Gotz, B Bouhemad, H Dokainish, C Bruch, C Bruch, Y Hadano, BP Paelinck, M McCulloch, MS Firstenberg, C Bruch, A Diwan, KA D'Souza, DA Tighe, VK Munagala, J De Sutter, A Prasad, JJ Remmen, DW Kitzman, JR Wilson, RJ MacFadyen, F Pedersen, LK Morrison, JW Ha, D Talreja, MI Burgess, Y Matsumura, CJ McMahon, JW Ha, N Smart, SH Lee, Y Hadano, NR Van de Veire, SJ Skaluba, AL Clark, JW Ha, PG Steg, MA Silver, CW Knudsen, CW Yancy, WF Peacock IV, D Logeart, S Dabbah, J Wang, H Dokainish, S Arques, S Arques, CW Knudsen, A Strunk, J Coste, S Arques, CH Huang   +105 more
core   +2 more sources

Left heart disease in pulmonary hypertension

, 2023
Pulmonary hypertension (PH) due to left heart disease (LHD) is the most common type of pulmonary hypertension. Pulmonary hypertension due to LHD has two subgroups: isolated post-capillary PH due to left sided filling pressures, and then in long-standing cases, the pre-capillary component is added due to pulmonary vascular disease developing, which is ...
Ellie Anderson, Mustapha Abubakar, Osman Imam Abbas Ahmed, Jonard Carpio, Rajwinder Nijjar, Ajay Suri   +5 more
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Assessment of Left Atrial Deformation and Function by 2-Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease [PDF]

, 2017
open7noBackground: The assessment of left atrial (LA) function by 2-dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs.
Baron Toaldo, M., Cipone, M., Contiero, B., Diana, A., Guglielmini, C., Pelle, N. G., Romito, G.   +6 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Mid-term echocardiographic follow up of left ventricular function with permanent right ventricular pacing in pediatric patients with and without structural heart disease

Cardiovascular Ultrasound, 2007
Background Chronic right ventricular apical pacing may have detrimental effect on left ventricular function and may promote to heart failure in adult patients with left ventricular dysfunction.
Kornyei Laszlo, Mihalcz Attila, Kardos Attila, Vatasescu Radu, Paprika Dora, Shalganov Tchavdar, Szatmari Andras, Szili-Torok Tamas   +7 more
doaj   +1 more source

Targeted therapy with phosphodiesterase 5 inhibitors in patients with pulmonary hypertension due to heart failure and elevated pulmonary vascular resistance: a systematic review

Pulmonary Circulation, 2020
Pulmonary Hypertension due to left heart disease is the most common type of Pulmonary Hypertension. Morbidity and mortality significantly increase once Pulmonary Hypertension is present.
Galo M. Sanchez Palacios, Cindy Schmidt, Tammy Wichman   +2 more
doaj   +1 more source

Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry [PDF]

, 2016
The establishment of left–right (L-R) asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during embryogenesis. Mutations in CCDC11 disrupt L-R asymmetry and cause congenital heart disease in humans, yet the molecular and ...
Betleja, Ewelina, John, Emily, Mahjoub, Moe R, Mitchell, Brian J, Moresco, James J, Silva, Erica, Spear, Philip, Yates, John R, III, Zhang, Siwei   +8 more
core   +2 more sources