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Legionella pneumophila can cause a potentially fatal form of humane pneumonia (Legionnaires' disease), which is most problematic in immunocompromised and in elderly people.
Martina Oder +5 more
doaj +1 more source
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases [PDF]
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie +20 more
core +4 more sources
Probable Person-to-Person Transmission of Legionnaires’ Disease [PDF]
Correspondence to the Editor.Legionnaires’ disease is an often severe form of pneumonia that is typically acquired by susceptible persons (e.g., elderly persons and smokers) through inhalation of aerosols that contain legionella species.1-4 A cluster of ...
Almeida, Sónia +16 more
core +1 more source
BackgroundThe detection rates of Legionella pneumophila in metro cooling tower water in various cities are relatively high, while studies investigating the trends of Legionella pneumophila pollution and analyzing its influencing factors are still limited.
Rong PENG +4 more
doaj +1 more source
Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
Ecological distribution of Legionella pneumophila [PDF]
Bacteria were concentrated 500-fold from 20-liter water samples collected from 67 different lakes and rivers in the United States. The data suggest that Legionella pneumophila is part of the natural aquatic environment and that the bacterium is capable of surviving extreme ranges of environmental conditions.
Fliermans, C. B. +5 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Advances in Double‐Stranded DNA Targeting Technologies
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen +8 more
wiley +1 more source
Distribution of Legionella and bacterial community composition among regionally diverse US cooling towers. [PDF]
Cooling towers (CTs) are a leading source of outbreaks of Legionnaires' disease (LD), a severe form of pneumonia caused by inhalation of aerosols containing Legionella bacteria.
Anna C Llewellyn +6 more
doaj +1 more source
Legionella pneumophila (L. pneumophila) is a gram-negative bacterium that replicates in a compartment that resembles the host endoplasmic reticulum (ER). To create its replicative niche, L.
Mio Kawabata +7 more
doaj +1 more source

