Symbiont-Mediated Defense against Legionella pneumophila in Amoebae
mBio, 2019 Bacterial pathogens are generally investigated in the context of disease. To prevent outbreaks, it is essential to understand their lifestyle and interactions with other microbes in their natural environment.
L. König +7 more
semanticscholar +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1994 Several reports have related Legionella pneumophila with pneumonia in renal transplant patients, however this association has not been systematically documented in Brazil.
Neusa Augusta de Oliveira Mazieri +5 more
doaj +1 more source
Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. [PDF]
, 2017 The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused on transcription induced by defined immunostimulatory ...
Barry, Kevin C +2 more
core +3 more sources
Whole genome sequence analysis reveals the broad distribution of the RtxA type 1 secretion system and four novel putative type 1 secretion systems throughout the Legionella genus. [PDF]
, 2020 Type 1 secretion systems (T1SSs) are broadly distributed among bacteria and translocate effectors with diverse function across the bacterial cell membrane. Legionella pneumophila, the species most commonly associated with Legionellosis, encodes a T1SS at
Brown, Connor L +7 more
core +2 more sources
Nature Microbiology, 2018 The bacterial pathogen Legionella pneumophila modulates host immunity using effectors translocated by its Dot/Icm transporter to facilitate its intracellular replication.
Ninghai Gan +3 more
semanticscholar +1 more source
How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]
, 2017 Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias +2 more
core +2 more sources
Legionella pneumophila Serogroup 1 in the Water Facilities of a Tertiary Healthcare Center, India
Emerging Infectious Diseases, 2017 Proactive environmental surveillance for Legionella pneumophila in hospitals that treat immunocompromised patients is a useful strategy for preventing nosocomial Legionnaires’ disease. We report the presence of L.
R. Chaudhry +4 more
semanticscholar +1 more source
Ubiquitination accomplished: E1 and E2 enzymes were not necessary [PDF]
, 2016 Qiu et al. (2016) show that a mono-ADP-ribosyltransferase, SdeA, from Legionella pneumophila catalyzes ADP-ribosylation of ubiquitin, allowing SdeA to modify substrate with ubiquitin in the absence of E1 and E2 ...
Huang, Danny T., Nakasone, Mark
core +1 more source
Evolution of the Arsenal of Legionella pneumophila Effectors To Modulate Protist Hosts
mBio, 2018 Within the human host, Legionella pneumophila replicates within alveolar macrophages, leading to pneumonia. However, L. pneumophila is an aquatic generalist pathogen that replicates within a wide variety of protist hosts, including amoebozoa, percolozoa,
Ashley Best, Y. Abu Kwaik
semanticscholar +1 more source
Ultrastructure of Legionella pneumophila. [PDF]
Journal of Clinical Pathology, 1979 Eleven lung samples positive for Legionnaires' disease, 12 strains of Legionella pneumophila cultured on various bacteriological media, and one strain growth in the yolk sac of fertile hens' eggs were examined by negative staining, thin sectioning, and scanning electron microscopy.
openaire +3 more sources