Results 61 to 70 of about 69,586 (312)

Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates

International Journal of Infectious Diseases
Objectives: The incidence of Legionnaires’ disease steadily increases worldwide. Although Legionella pneumophila is known as pathogenic, systematic investigations into antibiotic resistance are scarce, and reports of resistance in isolates are recently ...
Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard   +7 more
doaj   +1 more source

The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases [PDF]

, 2013
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie, Bode, Edna, Bode, Helge Björn, Bonge, Andreas, Daniel, Rolf, Dierking, Katja, Haack, Frederike Svenja, Hornung, Claudia, Jung, Kirsten, Krohn-Molt, Ines, Plener, Laure, Poehlein, Anja, Pohlen, Andrea, Pommerening-Röser, Andreas, Schmeißer, Christel, Schmidt, Martina, Schulenburg, Hinrich, Spieck, Eva, Streit, Wolfgang R., Timmermann, Gabriele, Utpatel, Christian   +20 more
core   +4 more sources

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

Molecular Systems Biology, 2016
Pathogens deliver complex arsenals of translocated effector proteins to host cells during infection, but the extent to which these proteins are regulated once inside the eukaryotic cell remains poorly defined.
M. Urbanus, A. Quaile, P. Stogios, M. Morar, Chitong Rao, Rosa Di Leo, E. Evdokimova, M. Lam, Christina Oatway, M. Cuff, J. Osipiuk, K. Michalska, B. Nocek, Mikko Taipale, A. Savchenko, Alexander W. Ensminger   +15 more
semanticscholar   +1 more source

Contamination of Legionella pneumophila in metro cooling tower water and its influencing factors in a city

环境与职业医学
BackgroundThe detection rates of Legionella pneumophila in metro cooling tower water in various cities are relatively high, while studies investigating the trends of Legionella pneumophila pollution and analyzing its influencing factors are still limited.
Rong PENG, Bin SHI, Huaiji WANG, Junling LIU, Fang WANG   +4 more
doaj   +1 more source

Metagenomic next-generation sequencing clinches the diagnosis of Legionella pneumonia in a patient with acute myeloid leukemia: A case report and literature review

Frontiers in Cellular and Infection Microbiology, 2022
Legionella pneumonia caused by Legionella pneumophila is a multi-system disease that is a life-threatening, acute, and severe form of pneumonia. L. pneumophila is widespread and the clinical manifestations of Legionella pneumonia are similar to those of ...
Siqiang Niu, Siqiang Niu, Siqiang Niu, Limin Zhao, Limin Zhao, Limin Zhao   +5 more
doaj   +1 more source

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle, Lieselotte eVande Walle, Mohamed eLamkanfi, Mohamed eLamkanfi   +3 more
core   +2 more sources

Hijacking of the Host Ubiquitin Network by Legionella pneumophila

Frontiers in Cellular and Infection Microbiology, 2017
Protein ubiquitination is critical for regulation of numerous eukaryotic cellular processes such as protein homeostasis, cell cycle progression, immune response, DNA repair, and vesicular trafficking.
Jiazhang Qiu, Zhao-qing Luo
semanticscholar   +1 more source

Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS

PLoS Pathogens, 2016
Legionella pneumophila is a facultative intracellular bacterium that lives in aquatic environments where it parasitizes amoeba. However, upon inhalation of contaminated aerosols it can infect and replicate in human alveolar macrophages, which can result ...
Pascal Ziltener, T. Reinheckel, A. Oxenius   +2 more
semanticscholar   +1 more source

Development and Validation of a High‐Throughput Screening Assay for the Legionella ADP‐Ribosyl Transferase SdeA

ChemBioChem, EarlyView.
We show the optimization and application of a fluorogenic assay to monitor Legionella SdeA activity in a High‐Throughput‐Screening campaign. Ubiquitination of proteins is one of the most crucial post‐translational modifications in eukaryotic cells, typically involving conjugation of ubiquitin to a lysine residue in a substrate using a three‐enzyme ...
Halana C. Vlaming, Vito Pol, Bjorn R. van Doodewaerd, Angeliki Moutsiopoulou, Paul P. Geurink, Robbert Q. Kim, Gerbrand J. van der Heden van Noort   +6 more
wiley   +1 more source

Molecular detection of Legionella: moving on from mip

Frontiers in Cellular and Infection Microbiology, 2010
The detection of Legionella pneumophila in environmental and clinical samples is frequently performed by PCR amplification of the mip and/or 16S rRNA genes. Combined with DNA sequencing, these two genetic loci can be used to distinguish different species
Stacey FY Yong, Stacey FY Yong, Shin Hwa eTan, Joanne eWee, Jing Jhi eTee, Fiona M Sansom, Hayley J Newton, Elizabeth L Hartland   +7 more
doaj   +1 more source