Results 61 to 70 of about 52,688 (260)

Molecular Respiratory Pathogen Panels in Lung Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Molecular respiratory pathogen panels are an innovative tool for the rapid detection of respiratory pathogens and antimicrobial resistance genes, offering the potential to improve diagnostic accuracy and guide timely antimicrobial therapy.
Andrea Lombardi
wiley   +1 more source

Distribution of Virulence Genes and Sequence-Based Types Among Legionella pneumophila Isolated From the Water Systems of a Tertiary Care Hospital in India

Frontiers in Public Health, 2020
Background: Legionnaires' disease (LD) is a potentially fatal pneumonia predominantly caused by infection due to Legionella pneumophila although more than 50 other Legionella species are described. Water systems contaminated with Legionella spp.
K. Sreenath, Rama Chaudhry, E. V. Vinayaraj, A. B. Dey, S. K. Kabra, Bhaskar Thakur, Randeep Guleria   +6 more
doaj   +1 more source

Metagenomic next-generation sequencing clinches the diagnosis of Legionella pneumonia in a patient with acute myeloid leukemia: A case report and literature review

Frontiers in Cellular and Infection Microbiology, 2022
Legionella pneumonia caused by Legionella pneumophila is a multi-system disease that is a life-threatening, acute, and severe form of pneumonia. L. pneumophila is widespread and the clinical manifestations of Legionella pneumonia are similar to those of ...
Siqiang Niu, Siqiang Niu, Siqiang Niu, Limin Zhao, Limin Zhao, Limin Zhao   +5 more
doaj   +1 more source

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]

, 1987
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core  

The Rab-binding profiles of bacterial virulence factors during infection [PDF]

, 2016
Legionella pneumophila, the causative agent of Legionnaire's disease, uses its type IV secretion system to translocate over 300 effector proteins into host cells.
Broncel, M, Carson, D, Frankel, GM, Mattheis, C, Mousnier, A, Schroeder, GN, So, EC, Tate, EW   +7 more
core   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, Volume 45, Issue 2, Page 392-428, March/April 2026.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

Severe Legionella pneumophila pneumonia treated with extracorporeal membrane oxygenation (ECMO): A case report

Journal of Education, Health and Sport, 2019
Legionella pneumophila is an aerobic, Gram-negative bacterium, whose natural environment are aquatic reservoirs. The source of infection may be also tap water, fountains and air-conditioners. Among young people, it can cause only mild infections, however
Paulina Kurdyś, Krystian Ślusarz, Ewa Trejnowska   +2 more
doaj   +3 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, Volume 16, Issue 2, Page 279-298, February 2026.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Contamination status and molecular typing of Legionella pneumophila in artificial water environment in Shanghai hospitals from 2019 to 2020

环境与职业医学, 2023
BackgroundThe incidence of Legionnaires' disease is increasing globally and artificial water environment is becoming a common source of outbreaks. Molecular typing techniques can help prevent and control Legionella.
Jiaying GAO, Lingyue YUAN, Yanxin CHEN, Yong CHEN, Jiayuan LUO, Mingliang CHEN, Min CHEN   +6 more
doaj   +1 more source

Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila. [PDF]

, 2013
BackgroundEvery genome contains a large number of uncharacterized proteins that may encode entirely novel biological systems. Many of these uncharacterized proteins fall into related sequence families. By applying sequence and structural analysis we hope
Aravind, L, Axelrod, Herbert L, Bateman, Alex, Chang, Yuanyuan, Coggill, Penelope, Das, Debanu, Eberhardt, Ruth Y, Finn, Robert D, Godzik, Adam, Jaroszewski, Lukasz, Murzin, Alexey G, Xu, Qingping   +11 more
core   +2 more sources