Results 71 to 80 of about 52,688 (260)

Torque Teno Virus Levels During Viral Respiratory Infections: The Interplay With Immune Dysregulation and Coagulopathy Biomarkers

open access: yesJournal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Torque teno virus (TTV) is a ubiquitous, nonenveloped DNA virus of the Anelloviridae family and a proposed surrogate marker of immune competence. Although nonpathogenic, its replication reflects host immune status and is associated with immune dysregulation during respiratory viral infections (RVIs).
Roberto Ferrarese   +13 more
wiley   +1 more source

Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. [PDF]

open access: yes, 2014
BackgroundBurkholderia pseudomallei is the causative agent of melioidosis, a potentially fatal disease endemic in Southeast Asia and Northern Australia.
Chen, Isabelle Gek Joo   +9 more
core   +2 more sources

Covalent Coercion by Legionella pneumophila [PDF]

open access: yesCell Host & Microbe, 2011
Adenylylation of Rab proteins appears to be an intriguing mechanism that Legionella pneumophila uses to modulate their activity during infection. Now the reverse reaction (deadenylylation) (Neunuebel et al., 2011; Tan and Luo, 2011) and a new posttranslational modification (phosphocholination) of Rab1 (Mukherjee et al., 2011) have been reported.
Itzen, A., Goody, R.
openaire   +3 more sources

The Burden of Respiratory Syncytial Virus in Children With Acute Otitis Media: A Systematic Review and Meta‐Analysis

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background Acute otitis media (AOM) affects over 709 million individuals globally each year, more than half of whom are children < 5 years. Respiratory syncytial virus (RSV) is a leading viral cause of pediatric respiratory illness. We aimed to estimate the burden of RSV in children < 5 years with AOM Methods We performed a systematic review ...
Sebastien Kenmoe   +4 more
wiley   +1 more source

Antimicrobial Susceptibility Determination of Less Frequently Isolated Legionella Species by Broth and Agar Dilution

open access: yesAntibiotics
Background/Objectives: Infections caused by Legionella species are primarily associated with Legionella pneumophila, but non-pneumophila species are increasingly implicated in human disease.
Caitlin Farley   +9 more
doaj   +1 more source

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]

open access: yes, 2018
Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M.   +5 more
core   +1 more source

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai   +5 more
wiley   +1 more source

Frequency Distribution of Legionella Pneumophila among Patients with Fever and Neutropenia in Seyedoshohada Hospital, Isfahan, Iran, during 2014-2015

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Legionella pneumophila is considered as one of the most important etiologies of respiratory infection in immunocompromised patients, which causes high morbidity and mortality.
Mohsen Meidani, Mohamadhosein Ashja
doaj  

Antibiotic resistance and genetic characteristics of Legionella pneumophila isolated from artificial water environment in Zhongshan from 2012 to 2024

open access: yes环境与职业医学
BackgroundThere is currently limited research on the antibiotic resistance of Legionella pneumophila in China. Establishing analytical methods for antibiotic resistance phenotypes and resistance genes of Legionella pneumophila in artificial water ...
Qiming LIU   +4 more
doaj   +1 more source

Extracellular enzymes of Legionella pneumophila [PDF]

open access: yesInfection and Immunity, 1981
All strains of Legionella pneumophila tested produced detectable levels of extracellular protease, phosphatase, lipase, deoxyribonuclease, ribonuclease, and beta-lactamase activity. Weak starch hydrolysis was also demonstrated for all strains. Elastase, collagenase, phospholipase C, hyaluronidase, chondroitinase, neuraminidase, or coagulase were not ...
T C, Thorpe, R D, Miller
openaire   +2 more sources

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