Results 81 to 90 of about 69,586 (312)
Frontiers in Microbiology, 2016 Legionella pneumophila, the major causative agent of Legionnaires’ disease, is found in freshwater environments in close association with free-living amoebae and multispecies biofilms, leading to persistence, spread, biocide resistance, and elevated ...
J. Berjeaud +7 more
semanticscholar +1 more source
Necrotrophic Growth of Legionella pneumophila [PDF]
Applied and Environmental Microbiology, 2006 ABSTRACT This study examined whether Legionella pneumophila is able to thrive on heat-killed microbial cells (necrotrophy) present in biofilms or heat-treated water systems. Quantification by means of plate counting, real-time PCR, and flow cytometry demonstrated necrotrophic growth of L ...
Verstraete, W. +4 more
openaire +5 more sources
Small, EarlyView.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. [PDF]
, 1987 Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative bacterium and a facultative intracellular parasite that multiplies in human monocytes and alveolar macrophages. In this paper, mutants of L.
Horwitz, MA
core
The Rab-binding profiles of bacterial virulence factors during infection [PDF]
, 2016 Legionella pneumophila, the causative agent of Legionnaire's disease, uses its type IV secretion system to translocate over 300 effector proteins into host cells.
Broncel, M +7 more
core +1 more source
ER remodeling by the large GTPase atlastin promotes vacuolar growth of Legionella pneumophila
EMBO Reports, 2017 The pathogenic bacterium Legionella pneumophila replicates in host cells within a distinct ER‐associated compartment termed the Legionella‐containing vacuole (LCV).
Bernhard Steiner +9 more
semanticscholar +1 more source
Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation
The FEBS Journal, EarlyView.This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley +1 more source
Journal of Education, Health and Sport, 2019 Legionella pneumophila is an aerobic, Gram-negative bacterium, whose natural environment are aquatic reservoirs. The source of infection may be also tap water, fountains and air-conditioners. Among young people, it can cause only mild infections, however
Paulina Kurdyś +2 more
doaj +3 more sources
Tropical Medicine and Infectious Disease, 2023 A Legionella pneumophila bacterium is ubiquitous in water distribution systems, including dental unit waterlines (DUWLs). Legionellosis is atypical pneumonia, including Legionnaires’ disease (LD) and the less acute form of Pontiac fever.
Ashraf R. Zayed +5 more
doaj +1 more source
Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core