Results 51 to 60 of about 554,776 (278)

Nano‐Gs‐Protein Peptidomimetika: Rationales Design von Peptiden, die vom C‐Terminus von Gα abgeleitet sind und Schlüsselkomponenten der Gs‐β2AR‐Wechselwirkungen nachahmen

open access: yesAngewandte Chemie, EarlyView.
G Protein‐gekoppelte Rezeptoren (GPCRs) sind wichtige therapeutische Zielstrukturen. Die Modulation der GPCR‐Aktivität über intrazelluläre Bindungsstellen gewinnt zunehmend an Bedeutung. Ein strukturell und computergestützter Ansatz ermöglichte die Entwicklung kleiner, vom G Protein abgeleiteter Peptidomimetika, die gezielt an die intrazelluläre ...
Phuong Thu Tran   +11 more
wiley   +1 more source

Bach and Opera: Is It Possible? [PDF]

open access: yes, 2012
Devoted to the art and science of technique, Johann Sebastian Bach (1685-1750) is a celebrated master of the musical genres of the time, except for opera.
Clark, Hilary
core   +1 more source

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

open access: yesAngewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran   +11 more
wiley   +1 more source

Tagungsbericht: "Hier sitze ich wieder in meiner Klause": Johann Gottfried Seume (1763 - 1810) und Leipzig [PDF]

open access: yes, 2010
Tagungsbericht: Veranstalter: Urs Meyer/ Gabi Pahnke, Johann-Gottfried-Seume-Gesellschaft zu Leipzig e.V.; Ludwig Stockinger, Universität Leipzig Datum, Ort: 03.06.2010-05.06.2010, Leipzig Bericht von: Urs Meyer, Universität Fribourg: Obgleich Johann ...
Meyer, Urs
core  

Application of symbol-operator technique for effective action computation

open access: yes, 2001
In the present talk we briefly demonstrate an elegant and effective technique for calculation of the trace expansion in the derivatives of background fields.
A. T. BANIN, N. G. PLETNEV, Pletnev N.G.
core   +1 more source

Mandible composition and properties in two selected praying mantises (Insecta, Mantodea)

open access: yesThe Anatomical Record, EarlyView.
Abstract Insects process their food with their cuticle‐based mouthparts. These feeding structures reflect their diversity and can, in some cases, showcase adaptations in material composition, mechanical properties, and shape to suit their specific dietary preferences.
Malo Roze   +3 more
wiley   +1 more source

Can Emotional Support Be Paid Forward with Charitable Donations? [PDF]

open access: yes, 2017
Paying it forward refers to the tendency for people who receive help from one person to help others in general later. Past research shows that instrumental support, which provides tangible benefits, can lead to paying it forward because of gratitude ...
Leipzig, Matthew
core  

Inter‐microscope comparability of dental microwear texture data obtained from different optical profilometers: Part II Deriving instrument‐specific correction equations for meta‐analyses using published data

open access: yesThe Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) has emerged as a valuable method for investigating the feeding ecology of vertebrates. Over the past decade, three‐dimensional topographic data from microscopic regions of tooth surfaces have been collected, and surface texture parameters have been published for both extant and fossil species.
Mugino O. Kubo   +4 more
wiley   +1 more source

Quasistationary collapse to the extreme Kerr black hole

open access: yes, 2004
It is shown that the extreme Kerr black hole is the only candidate for a black hole limit of rotating fluid bodies in equilibrium.Comment: 6 pages, submitted to Annalen der Physik ...
Meinel, Reinhard
core   +1 more source

Summary of the evaluation of the seminar „The effective library” [PDF]

open access: yes, 2002
The seminar in Leipzig was the 10th Seminar of The LIBER Architecture Group. During the years the Architecture Group has tried to organize the seminars in different ways, but every time with a strong focus on presentation of projects, library visits ...
Notten, Tanja
core   +2 more sources

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