Results 41 to 50 of about 295,484 (251)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Koenen, Erik (Hrsg.) (2016): Die Entdeckung der Kommunikationswissenschaft. 100 Jahre kommunikationswissenschaftliche Fachtradition in Leipzig: Von der Zeitungskunde zur Kommunikations- und Medienwissenschaft.

Studies in Communication Sciences, 2017
Der von Erik Koenen herausgegebene Band, der im Kontext des hundertjährigen Jubiläums des Leipziger Instituts für Kommunikations- und Medienwissenschaft (IfKMW) entstanden ist, zeichnet auf einer ersten Ebene die organisatorische Entwicklung des ...
Mike Meißner
doaj   +1 more source

Developing a Mobile Health Application to Communicate Adverse Drug Reactions – Preconditions, Assessment of Possible Functionalities and Barriers for Patients and Their General Practitioners

Journal of Multidisciplinary Healthcare, 2022
Ines Wakob,1,2 Gordian Lukas Schmid,3 Ingo Nöhring,3 Romy Elze,4 Ralf Sultzer,5 Thomas Frese,6 Susanne Schiek,1,2,* Thilo Bertsche1,2,* 1Clinical Pharmacy, Institute of Pharmacy, Medical Faculty, Leipzig University, Leipzig, Germany; 2Drug Safety
Wakob I, Schmid GL, Nöhring I, Elze R, Sultzer R, Frese T, Schiek S, Bertsche T   +7 more
doaj  

High‐Pressure Modulation of Breathing Kagome Lattice: Cascade of Lifshitz Transitions and Evolution of the Electronic Structure

Advanced Science, EarlyView.
External pressure directly tunes the breathing distortion of the kagome lattice in Fe3Sn2, suppressing it near 15 GPa and reversing it at higher pressures. This structural modulation drives a cascade of Lifshitz transitions, reconstructs the Fermi surface, strengthens electronic correlations and carrier localization, and modifies ultrafast electron ...
Marcos Vinicius Gonçalves‐Faria, Maxim Wenzel, Yuk Tai Chan, Olga Iakutkina, Francesco Capitani, Davide Comboni, Michael Hanfland, Qi Wang, Hechang Lei, Martin Dressel, Alexander A. Tsirlin, Alexej Pashkin, Stephan Winnerl, Manfred Helm, Ece Uykur   +14 more
wiley   +1 more source

Invasive Growth of Ailanthus altissima Trees is Associated with a High Rate of Sensitization in Atopic Patients

Journal of Asthma and Allergy, 2022
Freerk Prenzel1,2 *, Regina Treudler1,3 *, Tobias Lipek,1,2 Maike vom Hove,1,2 Paula Kage,1,3 Simone Kuhs,1,4 Thorsten Kaiser,1,4 Maximilian Bastl,5 Jan Bumberger,6– 8 Jon Genuneit,9,10 Thomas Hornick,8,11 Stefan Klotz,8,12 Julia Zarnowski,1,3 ...
Prenzel F, Treudler R, Lipek T, vom Hove M, Kage P, Kuhs S, Kaiser T, Bastl M, Bumberger J, Genuneit J, Hornick T, Klotz S, Zarnowski J, Boege M, Zebralla V, Simon JC, Dunker S   +16 more
doaj  

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

“Importing” the Enlightenment and “Enlightenment at the margins”. The example of Bohemia as a language and religious frontier, 1770-1800

Cornova
This contribution explores the hypothesis that 18th-century Bohemia, which was effectively a political and informational periphery directed from Vienna, also functioned – thanks to its geographical position and other factors and despite unfavourable ...
Daniela Tinková
doaj   +1 more source

Fluorescence in situ Hybridization (FISH) in the Microbiological Diagnostic of Deep Sternal Wound Infection (DSWI)

Infection and Drug Resistance, 2021
Nick Spindler,1 Annette Moter,2,3 Alexandra Wiessner,2,3 Tanja Gradistanac,4 Michael Borger,5 Arne C Rodloff,6 Stefan Langer,1 Judith Kikhney2,3 1Department of Orthopedic Surgery, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig ...
Spindler N, Moter A, Wiessner A, Gradistanac T, Borger M, Rodloff AC, Langer S, Kikhney J   +7 more
doaj  

Integration of Redox‐Active Polyoxovanadate Clusters into PMMA: Structure, Nanoscale Organization and Multilevel Redox Switching

Advanced Electronic Materials, EarlyView.
Solvent‐processable polyoxovanadate–PMMA nanocomposites exhibit concentration‐dependent 2D and 3D organization on gold surfaces, while retaining multilevel redox switching at room temperature. These hybrids bridge nanoscale functionality and macroscopic measurement, establishing a versatile platform for hybrid molecular–polymer memory materials ...
Jonas Lorenz, Marco Moors, Tom Scherzer, Olesya Daikos, Jens Bauer, Andrea Prager, Jan Griebel, Yeji Lee, Vineeth Kumar Bandari, Thomas Blaudeck, Oliver G. Schmidt, Kirill Monakhov   +11 more
wiley   +1 more source

Treatment of Supraophthalmic Internal Carotid Artery Fenestration with an Associated Aneurysm via Flow Diversion: A Case Report

International Medical Case Reports Journal, 2021
Johannes Kasper,1 Ulf Nestler,1 Jürgen Meixensberger,1 Ulf Quäschling2 1Department of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany; 2Institute of Neuroradiology, Department of Diagnostic Medicine, University Hospital Leipzig ...
Kasper J, Nestler U, Meixensberger J, Quäschling U   +3 more
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