Results 91 to 100 of about 152,189 (278)

Production of Recombinant Leishmania Tropica Parasites Expressing Two Proteins of Egfp and Luciferase Reporter

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: L. tropica is the major cause of cutaneous and visceral leishmaniasis in Iran. Due to lack of an accurate, sensitive and noninvasive detection test in animal model is a major problem. Here, we designed L.
T Taheri, M Eskandar, S Rafati
doaj  

Chemoinformatics Strategies for Leishmaniasis Drug Discovery

Frontiers in Pharmacology, 2018
Leishmaniasis is a fatal neglected tropical disease (NTD) that is caused by more than 20 species of Leishmania parasites. The disease kills approximately 20,000 people each year and more than 1 billion are susceptible to infection. Although counting on a
Leonardo L. G. Ferreira, Adriano D. Andricopulo   +1 more
doaj   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Leishmania in synanthropic rodents (Rattus rattus): new evidence for the urbanization of Leishmania (Leishmania) amazonensis [PDF]

Revista Brasileira de Parasitologia Veterinária, 2017
Abstract This study aimed to detect parasites from Leishmania genus, to determine the prevalence of anti-Leishmania spp. antibodies, to identify circulating species of the parasite, and to determine epidemiological variables associated with infection in rats caught in urban area of Londrina, Paraná, Brazil.
Caldart, Eloiza Teles, Freire, Roberta Lemos, Ferreira, Fernanda Pinto, Ruffolo, Bruno Bergamo, Sbeghen, Mônica Raquel, Mareze, Marcelle, Garcia, João Luis, Mitsuka-Breganó, Regina, Navarro, Italmar Teodorico   +8 more
openaire   +6 more sources

Kinetoplastids:related protozoan pathogens, different diseases [PDF]

, 2008
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Agranoff, Alan Fairlamb, Albrecht, Ambroise-Thomas, Andrade, Armijos, Atwood, Avila, Balana-Fouce, Benchimol Barbosa, Bern, Berriman, Bhattacharya, Bhattacharya, Bisser, Brun, Burleigh, Burns, Burri, Campos-Neto, Castro, Chava, Cohen, Coler, Coler, Coler, Combs, Croft, da Costa, de Castro, De Luca, de Macedo, Deborggraeve, Deng, Denkers, Dias, Doyle, Eastman, El Kouni, El-Sayed, Engel, Engers, Enserink, Ferguson, Frearson, Genaro, Ghalib, Ghalib, Gorczynski, Grazia, Grevelink, Guler, Gurtler, Gurtler, Gurtler, Gürtler, Hammarton, Hawn, Heby, Hopkins, Houghton, Jim McKerrow, Jones, Ken Stuart, Kgori, Khalil, Khalil, Krauth-Siegel, Kroeger, Kropf, Launois, Lee, Lejon, Lohoff, Magnus, Marsden, Marth, Martin, Mayrink, Mazurek, McConville, Molina, Nare, Nwaka, Nylen, Olliaro, Opperdoes, Ouellette, Panethymitaki, Picollo, Pirard, Radwanska, Radwanska, Ramesh, Reed, Reed, Reiner, Reithinger, Reithinger, Renslo, Reto Brun, Ricardo E. Gürtler, Rick Tarleton, Sadeghian, Scharton-Kersten, Schmid, Schnaufer, Simon Croft, Skeiky, Sosa, Soto, Steve Reed, Stuart, Sundar, Sundar, Tarleton, Tarleton, Tarleton, Thakur, Torr, Urbina, Viotti, Viotti, Welburn, Werbovetz, Xong, Young, Zijlstra   +127 more
core   +3 more sources

Determining Leishmania Infection Levels by Automatic Analysis of Microscopy Images [PDF]

arXiv, 2013
Analysis of microscopy images is one important tool in many fields of biomedical research, as it allows the quantification of a multitude of parameters at the cellular level. However, manual counting of these images is both tiring and unreliable and ultimately very time-consuming for biomedical researchers.
arxiv  

Genome-wide quantification of polycistronic transcription in Leishmania major

mBio
Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year.
Janne Grünebast, Stephan Lorenzen, Joachim Clos   +2 more
doaj   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Leishmaniasis (LI) is a vector‐borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe the characteristics of patients with IBD who present with leishmaniasis, infection outcomes and the risk factors associated with ...
L Madero‐Velázquez, A Mínguez, L Mayorga, JJ Ramírez, N Moreno, C Amorós, MA Nieto, R Mena, JM Benítez, L Gimeno‐Pitarch, N Maroto, C Suria, F Rodríguez‐Moranta, I Ordás, L Ruiz, MA García‐Brenes, A Martín‐Cardona, C Rubín de Célix, K Cárdenas, D Ginard, L Medina, N Pedrero, R Plaza, R Salmoral, TJ Martínez‐Pérez, V Algara, E Merino, Y Zabana, A Gutiérrez, on behalf of Young Group of GETECCU   +29 more
wiley   +1 more source

Selective effects of Euterpe oleracea (açai) on Leishmania (Leishmania) amazonensis and Leishmania infantum

Biomedicine & Pharmacotherapy, 2018
Leishmania (Leishmania) amazonensis and Leishmania infantum (=Leishmania chagasi) are protozoa that cause American cutaneous and visceral leishmaniasis, respectively. These diseases show a high incidence in developing countries such as Brazil. The treatments used for leishmaniasis are still limited due to their high cost and toxicity.
Hervé Rogez, Edilene O. Silva, Edilene O. Silva, Bruno José Martins Da Silva, Bruno José Martins Da Silva, Maria Elena Crespo-Lopez, José Rogério Souza-Monteiro, José Luiz Martins do Nascimento, José Luiz Martins do Nascimento   +8 more
openaire   +3 more sources