Results 101 to 110 of about 97,027 (246)
BackgroundCutaneous leishmaniasis (CL), caused by Leishmania (L.) species, remains a neglected tropical disease in many developing countries. We and others have shown that different Leishmania species can alter the gene expression profile of human host ...
Shima Hadifar +10 more
doaj +1 more source
The observation that differentiation of parasite life cycle stages involves structural and functional reorganisation is very familiar. A recent paper by Besteiro and colleagues provides an intriguing insight into cellular remodelling during differentiation.
openaire +2 more sources
Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review
Significant populations in tropical and sub-tropical locations all over the world are severely impacted by a group of neglected tropical diseases called leishmaniases.
Natáli T. Capistrano Costa +7 more
doaj +1 more source
Chicken blood provides a suitable meal for the sand fly Lutzomyia longipalpis and does not inhibit Leishmania development in the gut [PDF]
Background The aim of this study was to address the role of chickens as bloodmeal sources for female Lutzomyia longipalpis and to test whether chicken blood is harmful to Leishmania parasite development within the sand flies.
Diaz-Albiter Hector M +27 more
core +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source
Species structure of sand fly (Diptera: Psychodidae) fauna in the Brazilian western Amazon
We surveyed areas of the state of Rondônia in western Amazon for phlebotomine, which are potential vectors of leishmaniasis. A total of 5,998 specimens were captured, resulting in the identification of 48 species within the Lutzomyia (99.98%) and ...
Luiz Herman Soares Gil +10 more
doaj +1 more source
Axenic cultivation and characterization of Leishmania mexicana amastigote-like forms [PDF]
A new method is described which has made possible the long-term axenic cultivation of Leishmania mexicana amastigote-like forms in Schneider's Drosophila medium supplemented with 20% (v/v) foetal calf serum.
Coombs, G H +3 more
core
Synthetic glycovaccine protects against the bite of leishmania-infected sand flies
Leishmaniasis is a vectorborne disease transmitted to human and other mammalian hosts by sand fly bite. In the present study, we show that immunization with Leishmania mexicana promastigote secretory gel (PSG) or with a chemically defined synthetic ...
Bates, Paul A. +14 more
core +1 more source
Functional analysis of leishmania cyclopropane fatty acid synthetase [PDF]
The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L.
Mottram Jeremy C. +39 more
core +1 more source
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang +8 more
wiley +1 more source

