Results 81 to 90 of about 120,500 (221)

Knowledge, attitudes and practices about Visceral leishmaniasis in three communes of Neiva, Huila

Revista Habanera de Ciencias Médicas, 2023
Introduction: Visceral leishmaniasis is a zoonotic disease transmitted by vectors of the Lutzomyia genus, distributed in 98 countries, including Colombia, which can cause a serious clinical picture that, in the absence of treatment, can be fatal ...
Paola Aranzazu Garzon Polania, Maria Camila Charry Camacho, Angel David Salas Medina, Maria Eugenia Hernández Valenzuela, Juan Carlos Zambrano Arteaga   +4 more
doaj  

Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

Molecules, 2019
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva, Helliton Patrick Cordovil Brigido, Kelly Cristina Oliveira de Albuquerque, Josiwander Miranda Carvalho, Jordano Ferreira Reis, Lara Vinhal Faria, Márlia Regina Coelho-Ferreira, Fernando Tobias Silveira, Agnaldo da Silva Carneiro, Sandro Percário, Andrey Moacir do Rosário Marinho, Maria Fâni Dolabela   +11 more
doaj   +1 more source

Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis in a Child With Coronary Artery Dilation and SARS‐CoV‐2 Positivity: Diagnostic Overlap With MIS‐C. A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Macrophage activation syndrome (MAS) can complicate systemic juvenile idiopathic arthritis (sJIA) evolving over weeks. With SARS‐CoV‐2 positivity and coronary dilation, MIS‐C cannot be excluded, and here the timeline and serology do not establish SARS‐CoV‐2 as the trigger.
Ayham Slimi, Haya Jaradat, Baraa Nassar, Fawzy M. Abunejma   +3 more
wiley   +1 more source

Regulatory T Cells in Health and Disease

MedComm, Volume 7, Issue 11, November 2026.
Regulatory T cells (Tregs) arise through distinct developmental pathways and adapt to specialized tissue niches to maintain immune tolerance, barrier integrity, and metabolic homeostasis. In disease, Tregs undergo context‐dependent changes, ranging from functional insufficiency and lineage instability in autoimmune, inflammatory, cardiovascular, and ...
Mingyi Li, Si Zhang, Tangchun Wu, Tingting Tang, Xiang Cheng   +4 more
wiley   +1 more source

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. [PDF]

, 2009
Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus.
Alasdair C Ivens, Ivens, Alasdair C, Maroof, Asher, Paul M Kaye, Depledge Daniel P., Depledge, DP, Ivens, AC, Depledge, Daniel P, Maroof Asher, Aziz Naveed, Evans, KJ, Smith, Deborah F, Kaye, PM, Maroof, A, Smith, DF, Aziz, Naveed, Daniel P Depledge, Naveed Aziz, Ivens Alasdair C., Asher Maroof, Krystal J Evans, Evans Krystal J., Kaye Paul M., Aziz, N, Evans, Krystal J, Smith Deborah F., Kaye, Paul M, Deborah F Smith   +27 more
core   +1 more source

Optimization of the Timing of Induction for the Assessment of Nitric Oxide Production in Leishmania major Infected Macrophage Cells

Iranian Journal of Parasitology, 2016
Background: The present study was conducted to investigate the optimized timing for macrophages induction and nitric oxide (NO) production against invading Leishmania parasite. Methods: The present study examined the murine macrophage cell line, B10R,
Somaye SADEGHI, Negar SEYED, Sima RAFATI, Tahereh TAHERI   +3 more
doaj  

Altered miRNA expression in the lesions of cutaneous leishmaniasis caused by L. major and L. tropica with insights into apoptosis regulation

Scientific Reports
Leishmaniasis is a vector-borne infectious disease that affects many subtropical countries. Leishmania (L.) major and L. tropica are among the old-world causative agents and cause cutaneous leishmaniasis (CL).
Taha Masoudsinaki, Shima Hadifar, Hamzeh Sarvnaz, Mohammad Farahmand, Nasrin Masoudzadeh, Vahid Mashayekhi Goyonlo, Mohammadali Kerachian, Reza Erfanian Salim, Mourad Barhoumi, Seyed Latif Mousavi Gargari, Hossein Heydari, Sima Rafati   +11 more
doaj   +1 more source

Precursor‐targeted immune‐mediated anaemia in a dog with concurrent haemoparasite seroreactivity: Diagnostic challenges and therapeutic response

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues, Ellen Cristina Araújo de Medeiros, João Alfredo Biagi Camargo Neto, Igor Luiz Salardani Senhorello, Suely Regina Mogami Bomfim, Nayro Xavier de Alencar   +5 more
wiley   +1 more source

Idiopathic immune‐mediated polyarthritis in a dog associated with ionised hypercalcaemia and probable ischaemic dermatopathy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old, spayed, female Shiba Inu was presented with a 6‐week history of reduced appetite, lethargy and generalised stiffness, which showed only limited improvement despite anti‐inflammatory treatment. The most significant clinical abnormalities were pyrexia, stiffness, pain on joint manipulation and cutaneous lesions. Laboratory findings
Jeanne Bergeat, Eddy Nassif, Sarah Berger, Isabelle Lagrange, Noëlle Cochet‐Faivre, Pierre Deshuillers, Maxime Kurtz   +6 more
wiley   +1 more source

Anaplastic cutaneous plasmacytoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva, Júlia Kaori Hayashi, Danielle Cavalcanti Carvalho de Diniz, Maria Lucia Gomes Lourenço, Luiz Henrique Araujo de Machado   +4 more
wiley   +1 more source