Results 61 to 70 of about 111,453 (186)

A Review of Next-Generation Plasmid Systems for the Design and Optimization of DNA Vaccines [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Vaccines are widely regarded as one of the greatest achievements of modern medicine. By substantially reducing the burden of infectious diseases, they have dramatically improved global public health and life expectancy.
Sima Habibzadeh   +3 more
doaj  

Addressing Behavioural Determinants of Cutaneous Leishmaniasis Through Community Dialogue in Kalu District, Ethiopia: A Mixed‐Methods Study

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Cutaneous leishmaniasis (CL) is a major public health challenge in Ethiopia, with 20–30,000 new cases annually. Limited awareness and misconceptions contribute to delayed care seeking, stigma, prolonged healing, and reduced uptake of preventive measures in CL‐endemic communities.
Takele Gezahegn Demie   +13 more
wiley   +1 more source

Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania.

open access: yes, 2006
Species of the subgenus Leishmania (Leishmania) cause the debilitating disease leishmaniasis on four continents. Species grouped within the Leishmania donovani complex cause visceral leishmaniasis, a life-threatening disease, often associated with ...
Mauricio, Isabel L   +6 more
core   +1 more source

Genome-wide quantification of polycistronic transcription in Leishmania major

open access: yesmBio
Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year.
Janne Grünebast   +2 more
doaj   +1 more source

Causes and Outcome of Systemic Inflammatory Response Syndrome in Dogs: An Observational Study of 172 Cases

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To evaluate the clinical characteristics, underlying diseases, organ dysfunctions, and survival of dogs with systemic inflammatory response syndrome (SIRS) or sepsis. Design Prospective observational study from January to December, 2023. Setting Single‐center, veterinary university teaching hospital.
Myriam A. Knopf   +10 more
wiley   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas   +8 more
wiley   +1 more source

Knowledge, attitudes and practices about Visceral leishmaniasis in three communes of Neiva, Huila

open access: yesRevista Habanera de Ciencias Médicas, 2023
Introduction: Visceral leishmaniasis is a zoonotic disease transmitted by vectors of the Lutzomyia genus, distributed in 98 countries, including Colombia, which can cause a serious clinical picture that, in the absence of treatment, can be fatal ...
Paola Aranzazu Garzon Polania   +4 more
doaj  

Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

open access: yesMolecules, 2019
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva   +11 more
doaj   +1 more source

A Preliminary Field Study to Evaluate the Efficacy of Spiramycin and Paromomycin Against Cattle Cryptosporidiosis

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction Cryptosporidium is responsible not only for large economic losses in the livestock sector, but also for high mortality in infants and immunocompromised people all over the world. Although multiple treatments have been tested in both animals and humans, no drug has yet been found to be 100% effective.
María Cristina Del Río   +6 more
wiley   +1 more source

Precursor‐targeted immune‐mediated anaemia in a dog with concurrent haemoparasite seroreactivity: Diagnostic challenges and therapeutic response

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues   +5 more
wiley   +1 more source

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