Results 61 to 70 of about 97,027 (246)

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

L-arginine deprivation impairs Leishmania major-specific T-cell responses. [PDF]

, 2009
The amino acid L-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing ...
Markus Munder, Beak‐San Choi, Munder, Markus, Kropf, Pascale, Choi, Beak-San, Rogers, Matthew, Matthew Rogers, Pascale Kropf   +7 more
core   +1 more source

Relationships Between European Wildcats and Domestic Cats in an Area of Sympatry: Exploring Key Conservation Questions on Hybridization and Disease Transmission

Animal Conservation, EarlyView.
We have found evidence of behavioural barriers for both hybridization and disease transmission between European wildcats and domestic cats. This includes hierarchical interspecies exclusion enforced by wildcats, as well as sexual selection exerted by wildcat females.
Jose María Gil‐Sánchez, Elena Bertos, Mariola Sánchez‐Cerdá, Emilio Virgós, Marcos Moleón   +4 more
wiley   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Production of Recombinant Leishmania Tropica Parasites Expressing Two Proteins of Egfp and Luciferase Reporter

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: L. tropica is the major cause of cutaneous and visceral leishmaniasis in Iran. Due to lack of an accurate, sensitive and noninvasive detection test in animal model is a major problem. Here, we designed L.
T Taheri, M Eskandar, S Rafati
doaj  

PUF Proteins as Critical RNA-Binding Proteins in TriTryp Parasites: A Review Article

Iranian Journal of Parasitology
In eukaryotes, translation is a fundamental step in the long pathway of protein synthesis within the cell. In this process, several proteins and factors have involved directly or indirectly, individually or in association with other elements to contact ...
Tahereh Taheri, Elaheh Davarpanah, Katayon Samimi-Rad, Negar Seyed   +3 more
doaj   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Detection of Leishmania RNA Virus in Leishmania Parasites

PLoS Neglected Tropical Diseases, 2013
Patients suffering from cutaneous leishmaniasis (CL) caused by New World Leishmania (Viannia) species are at high risk of developing mucosal (ML) or disseminated cutaneous leishmaniasis (DCL). After the formation of a primary skin lesion at the site of the bite by a Leishmania-infected sand fly, the infection can disseminate to form secondary lesions ...
Zangger, Haroun, Ronet, Catherine, Desponds, Chantal, Kuhlmann, F. Matthew, Robinson, John, Hartley, Mary-Anne, Prevel, Florence, Castiglioni, Patrik, Pratlong, Francine, Bastien, Patrick, Müller, Norbert, Parmentier, Laurent, Saravia, Nancy Gore, Beverley, Stephen, Fasel, Nicolas   +14 more
openaire   +10 more sources

The Leishmania donovani complex: genotypes of five metabolic enzymes (ICD, ME, MPI, G6PDH, and FH), new targets for multilocus sequence typing.

, 2007
Flagellates of the Leishmania donovani complex are causative agents of human cutaneous and visceral leishmaniasis. The complex is comprised of L. donovani, Leishmania infantum and Leishmania archibaldi, although the latter is not now considered to be a ...
Jirků, Milan, Mauricio, Isabel L, Zemanová, Eva, Lukes, Julius, Miles, Michael A, Horák, Ales   +5 more
core   +1 more source

Molecular approaches for a better understanding of the epidemiology and population genetics of Leishmania. [PDF]

, 2011
Molecular approaches are being used increasingly for epidemiological studies of visceral and cutaneous leishmaniases. Several molecular markers resolving genetic differences between Leishmania parasites at species and strain levels have been developed to
Kuhls, K, Schönian, G, Mauricio, IL
core   +1 more source