Results 41 to 50 of about 97,027 (246)

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

Food Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna, Hemant Sharma, Sonam Verma, Amar Jeet, Sumit Kumar Singh, Sharad Kumar Tripathi, Vedpriya Arya   +6 more
wiley   +1 more source

Lactococcus lactis as a Live-Vector Vaccine Platform for Parasitic Diseases

Journal of Medical Microbiology and Infectious Diseases
The development of expression systems using non-pathogenic microorganisms has enabled efficient and safe platforms for medical and food applications, including functional foods with therapeutic benefits. Among non-pathogenic bacteria, Lactococcus lactis (
Elaheh Davarpanah, Negar Seyed, Tahereh Taheri *   +2 more
doaj   +1 more source

Translating Observations From Leishmanization Into Non-Living Vaccines: The Potential of Dendritic Cell-Based Vaccination Strategies Against Leishmania

Frontiers in Immunology, 2018
Leishmaniasis is a health-threatening vector-borne disease in almost 90 different countries. While a prophylactic human vaccine is not yet available, the fact that recovery from leishmaniasis establishes lifelong immunity against secondary infection ...
Negar Seyed, Nathan C. Peters, Sima Rafati   +2 more
doaj   +1 more source

Current Status of Regulatory Non-Coding RNAs Research in the Tritryp

Non-Coding RNA, 2022
Trypanosomatids are protozoan parasites that cause devastating vector-borne human diseases. Gene expression regulation of these organisms depends on post-transcriptional control in responding to diverse environments while going through multiple ...
Rafael Sebastián Fort, Santiago Chavez, Juan M. Trinidad Barnech, Carolina Oliveira-Rizzo, Pablo Smircich, José Roberto Sotelo-Silveira, María Ana Duhagon   +6 more
doaj   +1 more source

Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival [PDF]

, 2009
All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites.
Podinovskaia, M, Rogers Matthew, Matthew Rogers, Rogers, Matthew E., Choi Beak-San, Choi, BS, Maria Podinovskaia, Kropf Pascale, Rogers, M, Bates, P, Dillon, R, Ingrid Müller, Kropf, P, Müller, Ingrid, Choi, B. S., Bates Paul, Podinovskaia, M., Kropf, P., Kropf, Pascale, Podinovskaia, Maria, Beak-San Choi, Rogers, Matthew, Dillon, Rod, Rod Dillon, Muller, I, Pascale Kropf, Dillon Rod, Bates, Paul, Müller Ingrid, Podinovskaia Maria, Choi, Beak-San, Paul Bates, Müller, I.   +32 more
core   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

RNA synthesis in Leishmania donovani is constitutive during stage conversion: a genome-wide PRO-seq analysis

Microbiology Spectrum
Transcription in Leishmania donovani has long been considered constitutive, as shown by nuclear run-on analyses and northern blots, with gene expression primarily regulated post-transcriptionally.
Janne Grünebast, Stephan Lorenzen, Christine Brinker, Annika Bea, Joachim Clos   +4 more
doaj   +1 more source

Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding [PDF]

Open Biology, 2017
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The evolutionary pressure associated with establishing and maintaining an infection and transmission to vector or host has shaped parasite morphology.
Jack Sunter, Keith Gull
doaj   +1 more source

Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania.

, 2006
Species of the subgenus Leishmania (Leishmania) cause the debilitating disease leishmaniasis on four continents. Species grouped within the Leishmania donovani complex cause visceral leishmaniasis, a life-threatening disease, often associated with ...
Mauricio, Isabel L, Figuerola, Jordi, Soriguer, Ramón C., Miles, Michael A, López, Guillermo, Stothard, J Russell, Gaunt, Michael W   +6 more
core   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source