Results 41 to 50 of about 120,500 (221)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. [PDF]

, 2009
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases.
Fitpatrick, S., Miles, M.A., Fitzpatrick, S, Mauricio, IL, Yeo, M., Gaunt, MW, Mauricio, I.L., Llewellyn, MS, Lewis, MD, Miles, MA, Baleela, R, Lewis, M.D., Gaunt, M.W., Yeo, M, Baleela, R., Llewellyn, M.S.   +15 more
core   +1 more source

Integrated One Health surveillance of human, canine and sand fly Leishmania infantum transmission in Sicily, southern Italy

Parasites & Vectors
Background Leishmaniasis is an endemic vector-borne disease in Sicily, sustained by Leishmania infantum, with dogs acting as the primary reservoir and phlebotomine sand flies as the main vectors.
Federica Bruno, Eugenia Oliveri, Francesco La Russa, Maria Liliana Di Pasquale, Roberto Hamel, Maria Clizia Di Patti, Maria Paola Maurelli, Laura Rinaldi, Gaetano Oliva, Giuseppe Pistone, Maria Rita Bongiorno, Carmelo Bongiorno, Fabrizio Vitale, Germano Castelli   +13 more
doaj   +1 more source

Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This study aims to synthesize and characterize lipid nanosystems (liposomes) for the incorporation of a Zn(II) porphyrin derivative, Zn(II) meso‐tetrakis(N‐n‐hexylpyridinium‐2‐yl)porphyrin (ZnTnHex‐2‐PyP4+, ZnPH), intending to employ an alternative method of treatment, such as photodynamic therapy (PDT), for breast cancer (BC ...
Kammila Martins Nicolau Costa, José Ferreira Sarmento‐Neto, Júlio Santos Rebouças, Ricardo Olímpio de Moura, John F. Callan, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

The Leishmania donovani complex: genotypes of five metabolic enzymes (ICD, ME, MPI, G6PDH, and FH), new targets for multilocus sequence typing.

, 2007
Flagellates of the Leishmania donovani complex are causative agents of human cutaneous and visceral leishmaniasis. The complex is comprised of L. donovani, Leishmania infantum and Leishmania archibaldi, although the latter is not now considered to be a ...
Jirků, Milan, Mauricio, Isabel L, Zemanová, Eva, Lukes, Julius, Miles, Michael A, Horák, Ales   +5 more
core   +1 more source

Leishmania naiffi and Leishmania guyanensis reference genomes highlight genome structure and gene evolution in the Viannia subgenus [PDF]

Royal Society Open Science, 2018
The unicellular protozoan parasite Leishmania causes the neglected tropical disease leishmaniasis, affecting 12 million people in 98 countries. In South America, where the Viannia subgenus predominates, so far only L. (Viannia) braziliensis and L.
Simone Coughlan, Ali Shirley Taylor, Eoghan Feane, Mandy Sanders, Gabriele Schonian, James A. Cotton, Tim Downing   +6 more
doaj   +1 more source

Eugenol-Rich Essential Oil from Pimenta dioica: In Vitro and In Vivo Potentialities against Leishmania amazonensis

Pharmaceuticals, 2023
Pimenta dioica L. is one the most recognized species with diverse biological activities. In this study, in vitro activity and in vivo efficacy of essential oil from P. dioica (EO-Pd) was evaluated.
Lianet Monzote, Laura Machín, Adiel González, Ramón Scull, Yamilet I. Gutiérrez, Prabodh Satyal, Lars Gille, William N. Setzer   +7 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Real-time PCR to differentiate among Leishmania (Viannia) subgenus, Leishmania (Leishmania) infantum and Leishmania (Leishmania) amazonensis: Application on Brazilian clinical samples

Acta Tropica, 2020
Leishmaniasis is a complex disease caused by Leishmania species belonging to subgenera Leishmania and Viannia. In South America, L. (L.) infantum is considered the most important causative agent of visceral leishmaniasis, while L. (L.) amazonensis and Viannia subgenus species are responsible for the different cutaneous or mucocutaneous forms.
Diotallevi, Aurora, Buffi, Gloria, Ceccarelli, Marcello, Neitzke-Abreu, Herintha Coeto, Gnutzmann, Laisa Vieira, da Costa Lima, Manoel Sebastião, Di Domenico, Alice, De Santi, Mauro, Magnani, Mauro, Galluzzi, Luca   +9 more
openaire   +3 more sources

Translating Observations From Leishmanization Into Non-Living Vaccines: The Potential of Dendritic Cell-Based Vaccination Strategies Against Leishmania

Frontiers in Immunology, 2018
Leishmaniasis is a health-threatening vector-borne disease in almost 90 different countries. While a prophylactic human vaccine is not yet available, the fact that recovery from leishmaniasis establishes lifelong immunity against secondary infection ...
Negar Seyed, Nathan C. Peters, Sima Rafati   +2 more
doaj   +1 more source