Results 31 to 40 of about 120,500 (221)
Scientific ReportsLeishmaniasis is a common parasitic infection in tropical regions worldwide, and yet there is no effective human vaccine available. The results of leishmanization in animal models have emphasized the role of antigen persistence after recovery from the ...
Negar Seyed +7 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Microbiology resource announcements, 2019 We present here the draft genome sequences of Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) mexicana, and Leishmania (Leishmania) aethiopica, potential etiological agents of diffuse cutaneous leishmaniasis (DCL). Sequence data were obtained using PacBio and MiSeq platforms.
Batra, Dhwani +7 more
openaire +2 more sources
Optimized Mouse BMDC Isolation and Culture under Endotoxin-Free Conditions
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021 Introduction: Dendritic cells are very important in basic studies and vaccine research, but isolation and culture of these cells face challenges due to their small number in tissues.
Atefeh Sadeghi Shermeh +4 more
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Frontiers in Immunology, 2022 Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania major infected THP-1 macrophages
Ismail Cem Yilmaz +14 more
doaj +1 more source
New Insights Into the Three‐Dimensional Mechanics of the Flagellar Beat Cycle
Cytoskeleton, EarlyView.ABSTRACT Advances in imaging at the molecular scale have provided greater detail concerning the three‐dimensional structure of the ciliary/flagellar axoneme. Additionally, it has recently been confirmed that electrostatic forces regulate the dynein‐tubulin interaction at the microtubule binding domain (MTBD) of dynein, and at the junction of the nexin ...
Charles B. Lindemann
wiley +1 more source
Immunity to Leishmania mexicana parasite [PDF]
, 2014 Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L.
Ali, KSM
core
Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania.
, 2006 Species of the subgenus Leishmania (Leishmania) cause the debilitating disease leishmaniasis on four continents. Species grouped within the Leishmania donovani complex cause visceral leishmaniasis, a life-threatening disease, often associated with ...
Mauricio, Isabel L +6 more
core +1 more source
Flavour and Fragrance Journal, EarlyView.This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez +2 more
wiley +1 more source
Inhibition of pteridine reductase 1 (PTR1) expression in Leishmania promastigotes using a full-length antisense construct [PDF]
, 2009 Leishmania exhibit many unusual features, one of which is the pteridine metabolic pathway essential for the growth for these parasites. Leishmania have evolved a complex and versatile pteridine salvage network capable of scavenging a wide array of ...
Nariman Mosaffa +7 more
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