Results 31 to 40 of about 172,432 (281)

The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host [PDF]

open access: yes, 2013
Bardet–Biedl syndrome (BBS) is a human genetic disorder with a spectrum of symptoms caused by primary cilium dysfunction. The disease is caused by mutations in one of at least 17 identified genes, of which seven encode subunits of the BBSome, a protein ...
Doehl, Johannes   +6 more
core   +1 more source

Visualization of Leishmania tropica Infection in BALB/c Mice by Bioluminescence Imaging

open access: yesIranian Biomedical Journal, 2020
Background: Leishmania tropica is the cause of more than one form of leishmaniasis and lacks a known reservoir animal. This study compares the potential infectivity of recombinant and wild-type L. tropica in BALB/c mice.
Mahdieh Eskandar   +6 more
doaj  

Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]

open access: yes, 2005
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea   +11 more
core   +1 more source

Leishmaniasis: new approaches to disease control. [PDF]

open access: yes, 2003
The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L   +3 more
core   +2 more sources

Optimized Mouse BMDC Isolation and Culture under Endotoxin-Free Conditions

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Dendritic cells are very important in basic studies and vaccine research, but isolation and culture of these cells face challenges due to their small number in tissues.
Atefeh Sadeghi Shermeh   +4 more
doaj  

Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia

open access: yesFrontiers in Immunology, 2022
Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania major infected THP-1 macrophages
Ismail Cem Yilmaz   +14 more
doaj   +1 more source

Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]

open access: yes, 1999
Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO   +8 more
core   +1 more source

Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. [PDF]

open access: yes, 2014
BACKGROUND: Visceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan.
Baleela, Rania   +6 more
core   +3 more sources

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

open access: yes, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S.   +3 more
core   +1 more source

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

open access: yesFood Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna   +6 more
wiley   +1 more source

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